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Toll-like receptor 2 is essential for the sensing of oxidants during inflammation.
Paul-Clark MJ, McMaster SK, Sorrentino R, Sriskandan S, Bailey LK, Moreno L, Ryffel B, Quesniaux VF, Mitchell JA. Paul-Clark MJ, et al. Among authors: mcmaster sk. Am J Respir Crit Care Med. 2009 Feb 15;179(4):299-306. doi: 10.1164/rccm.200707-1019OC. Epub 2008 Nov 14. Am J Respir Crit Care Med. 2009. PMID: 19011150 Free PMC article.
Selective NOD1 agonists cause shock and organ injury/dysfunction in vivo.
Cartwright N, Murch O, McMaster SK, Paul-Clark MJ, van Heel DA, Ryffel B, Quesniaux VF, Evans TW, Thiemermann C, Mitchell JA. Cartwright N, et al. Among authors: mcmaster sk. Am J Respir Crit Care Med. 2007 Mar 15;175(6):595-603. doi: 10.1164/rccm.200608-1103OC. Epub 2007 Jan 18. Am J Respir Crit Care Med. 2007. PMID: 17234906
Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll-like receptor 4 responses in macrophages.
Moreno L, McMaster SK, Gatheral T, Bailey LK, Harrington LS, Cartwright N, Armstrong PC, Warner TD, Paul-Clark M, Mitchell JA. Moreno L, et al. Among authors: mcmaster sk. Br J Pharmacol. 2010 Aug;160(8):1997-2007. doi: 10.1111/j.1476-5381.2010.00814.x. Br J Pharmacol. 2010. PMID: 20649597 Free PMC article.