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Page 1
Discovery of N-substituted 7-azaindoles as PIM1 kinase inhibitors - Part I.
Bioorg Med Chem Lett. 2017 Oct 15;27(20):4730-4734. doi: 10.1016/j.bmcl.2017.08.069. Epub 2017 Sep 18.
Bioorg Med Chem Lett. 2017.
PMID: 28947155
Molecular Basis of Action of a Small-Molecule Positive Allosteric Modulator Agonist at the Type 1 Cholecystokinin Holoreceptor.
Desai AJ, Mechin I, Nagarajan K, Valant C, Wootten D, Lam PCH, Orry A, Abagyan R, Nair A, Sexton PM, Christopoulos A, Miller LJ.
Desai AJ, et al. Among authors: mechin i.
Mol Pharmacol. 2019 Mar;95(3):245-259. doi: 10.1124/mol.118.114082. Epub 2018 Dec 27.
Mol Pharmacol. 2019.
PMID: 30591538
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The crystal structures of eukaryotic phosphofructokinases from baker's yeast and rabbit skeletal muscle.
Banaszak K, Mechin I, Obmolova G, Oldham M, Chang SH, Ruiz T, Radermacher M, Kopperschläger G, Rypniewski W.
Banaszak K, et al. Among authors: mechin i.
J Mol Biol. 2011 Mar 25;407(2):284-97. doi: 10.1016/j.jmb.2011.01.019. Epub 2011 Jan 15.
J Mol Biol. 2011.
PMID: 21241708
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Evaluation of cancer dependence and druggability of PRP4 kinase using cellular, biochemical, and structural approaches.
Gao Q, Mechin I, Kothari N, Guo Z, Deng G, Haas K, McManus J, Hoffmann D, Wang A, Wiederschain D, Rocnik J, Czechtizky W, Chen X, McLean L, Arlt H, Harper D, Liu F, Majid T, Patel V, Lengauer C, Garcia-Echeverria C, Zhang B, Cheng H, Dorsch M, Huang SA.
Gao Q, et al. Among authors: mechin i.
J Biol Chem. 2013 Oct 18;288(42):30125-30138. doi: 10.1074/jbc.M113.473348. Epub 2013 Sep 3.
J Biol Chem. 2013.
PMID: 24003220
Free PMC article.
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The structural basis for catalysis and specificity of the X-prolyl dipeptidyl aminopeptidase from Lactococcus lactis.
Rigolet P, Mechin I, Delage MM, Chich JF.
Rigolet P, et al. Among authors: mechin i.
Structure. 2002 Oct;10(10):1383-94. doi: 10.1016/s0969-2126(02)00851-1.
Structure. 2002.
PMID: 12377124
Free article.
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Structure of the reduced disulfide-bond isomerase DsbC from Escherichia coli.
Banaszak K, Mechin I, Frost G, Rypniewski W.
Banaszak K, et al. Among authors: mechin i.
Acta Crystallogr D Biol Crystallogr. 2004 Oct;60(Pt 10):1747-52. doi: 10.1107/S0907444904018359. Epub 2004 Sep 23.
Acta Crystallogr D Biol Crystallogr. 2004.
PMID: 15388920
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The 10.8-A structure of Saccharomyces cerevisiae phosphofructokinase determined by cryoelectron microscopy: localization of the putative fructose 6-phosphate binding sites.
Ruiz T, Mechin I, Bär J, Rypniewski W, Kopperschläger G, Radermacher M.
Ruiz T, et al. Among authors: mechin i.
J Struct Biol. 2003 Aug;143(2):124-34. doi: 10.1016/s1047-8477(03)00140-0.
J Struct Biol. 2003.
PMID: 12972349
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