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Development of improved PPARβ/δ inhibitors.
Toth PM, Naruhn S, Pape VF, Dörr SM, Klebe G, Müller R, Diederich WE. Toth PM, et al. Among authors: naruhn s. ChemMedChem. 2012 Jan 2;7(1):159-70. doi: 10.1002/cmdc.201100408. Epub 2011 Oct 24. ChemMedChem. 2012. PMID: 22025402
Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion.
Adhikary T, Brandt DT, Kaddatz K, Stockert J, Naruhn S, Meissner W, Finkernagel F, Obert J, Lieber S, Scharfe M, Jarek M, Toth PM, Scheer F, Diederich WE, Reinartz S, Grosse R, Müller-Brüsselbach S, Müller R. Adhikary T, et al. Among authors: naruhn s. Oncogene. 2013 Oct 31;32(44):5241-52. doi: 10.1038/onc.2012.549. Epub 2012 Dec 3. Oncogene. 2013. PMID: 23208498 Free PMC article.