Pritchard MC[au] - Search Results

Year	Number of Results
1991	1
1992	1
1993	1
1994	3
1995	1
1996	4
1997	1
1998	2
2000	1
2001	2
2023	1
2024	0

1

The therapeutic landscape of tauopathies: challenges and prospects.

Cummings JL, Gonzalez MI, Pritchard MC, May PC, Toledo-Sherman LM, Harris GA. Cummings JL, et al. Among authors: pritchard mc. Alzheimers Res Ther. 2023 Oct 6;15(1):168. doi: 10.1186/s13195-023-01321-7. Alzheimers Res Ther. 2023. PMID: 37803386 Free PMC article. Review.

2

PD 176252--the first high affinity non-peptide gastrin-releasing peptide (BB2) receptor antagonist.

Ashwood V, Brownhill V, Higginbottom M, Horwell DC, Hughes J, Lewthwaite RA, McKnight AT, Pinnock RD, Pritchard MC, Suman-Chauhan N, Webb C, Williams SC. Ashwood V, et al. Among authors: pritchard mc. Bioorg Med Chem Lett. 1998 Sep 22;8(18):2589-94. doi: 10.1016/s0960-894x(98)00462-4. Bioorg Med Chem Lett. 1998. PMID: 9873586

3

Use of a dipeptide chemical library in the development of non-peptide tachykinin NK3 receptor selective antagonists.

Boden P, Eden JM, Hodgson J, Horwell DC, Hughes J, McKnight AT, Lewthwaite RA, Pritchard MC, Raphy J, Meecham K, Ratcliffe GS, Suman-Chauhan N, Woodruff GN. Boden P, et al. Among authors: pritchard mc. J Med Chem. 1996 Apr 12;39(8):1664-75. doi: 10.1021/jm950892r. J Med Chem. 1996. PMID: 8648606

4

Two classes of structurally different antagonists display similar species preference for the human tachykinin neurokinin3 receptor.

Chung FZ, Wu LH, Tian Y, Vartanian MA, Lee H, Bikker J, Humblet C, Pritchard MC, Raphy J, Suman-Chauhan N, et al. Chung FZ, et al. Among authors: pritchard mc. Mol Pharmacol. 1995 Oct;48(4):711-6. Mol Pharmacol. 1995. PMID: 7476898

5

Rational design of high affinity tachykinin NK2 receptor antagonists.

Boyle S, Guard S, Hodgson J, Horwell DC, Howson W, Hughes J, McKnight A, Martin K, Pritchard MC, Watling KJ, et al. Boyle S, et al. Among authors: pritchard mc. Bioorg Med Chem. 1994 Feb;2(2):101-13. doi: 10.1016/s0968-0896(00)82006-4. Bioorg Med Chem. 1994. PMID: 7922121

6

Utilization of an intramolecular hydrogen bond to increase the CNS penetration of an NK(1) receptor antagonist.

Ashwood VA, Field MJ, Horwell DC, Julien-Larose C, Lewthwaite RA, McCleary S, Pritchard MC, Raphy J, Singh L. Ashwood VA, et al. Among authors: pritchard mc. J Med Chem. 2001 Jul 5;44(14):2276-85. doi: 10.1021/jm010825z. J Med Chem. 2001. PMID: 11428921

7

Rationally designed "dipeptoid" analogues of CCK. Acid mimics of the potent and selective non-peptide CCK-B receptor antagonist CI-988.

Drysdale MJ, Pritchard MC, Horwell DC. Drysdale MJ, et al. Among authors: pritchard mc. J Med Chem. 1992 Jul 10;35(14):2573-81. doi: 10.1021/jm00092a007. J Med Chem. 1992. PMID: 1635058

8

Cholecystokinin B antagonists. Synthesis and quantitative structure-activity relationships of a series of C-terminal analogues of CI-988.

Augelli-Szafran CE, Horwell DC, Kneen C, Ortwine DF, Pritchard MC, Purchase TS, Roth BD, Trivedi BK, Hill D, Suman-Chauhan N, Webdale L. Augelli-Szafran CE, et al. Among authors: pritchard mc. Bioorg Med Chem. 1996 Oct;4(10):1733-45. doi: 10.1016/0968-0896(96)00185-x. Bioorg Med Chem. 1996. PMID: 8931944

9

The influence of guanyl nucleotide on agonist and antagonist affinity at guinea-pig CCK-B/gastrin receptors: binding studies using [3H]PD140376.

Suman-Chauhan N, Meecham KG, Webdale L, Hunter JC, Pritchard MC, Woodruff GN, Hill DR. Suman-Chauhan N, et al. Among authors: pritchard mc. Regul Pept. 1996 Aug 27;65(1):37-43. doi: 10.1016/0167-0115(96)00070-5. Regul Pept. 1996. PMID: 8876034

10

Second generation "peptoid" CCK-B receptor antagonists: identification and development of N-(adamantyloxycarbonyl)-alpha-methyl-(R)-tryptophan derivative (CI-1015) with an improved pharmacokinetic profile.

Trivedi BK, Padia JK, Holmes A, Rose S, Wright DS, Hinton JP, Pritchard MC, Eden JM, Kneen C, Webdale L, Suman-Chauhan N, Boden P, Singh L, Field MJ, Hill D. Trivedi BK, et al. Among authors: pritchard mc. J Med Chem. 1998 Jan 1;41(1):38-45. doi: 10.1021/jm970065l. J Med Chem. 1998. PMID: 9438020

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