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Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimer's disease.
Yeap J, Sathyaprakash C, Toombs J, Tulloch J, Scutariu C, Rose J, Burr K, Davies C, Colom-Cadena M, Chandran S, Large CH, Rowan MJM, Gunthorpe MJ, Spires-Jones TL. Yeap J, et al. Among authors: sathyaprakash c. Brain Neurosci Adv. 2022 Mar 24;6:23982128221086464. doi: 10.1177/23982128221086464. eCollection 2022 Jan-Dec. Brain Neurosci Adv. 2022. PMID: 35359460 Free PMC article.
Impairment of Mitochondrial Calcium Buffering Links Mutations in C9ORF72 and TARDBP in iPS-Derived Motor Neurons from Patients with ALS/FTD.
Dafinca R, Barbagallo P, Farrimond L, Candalija A, Scaber J, Ababneh NA, Sathyaprakash C, Vowles J, Cowley SA, Talbot K. Dafinca R, et al. Among authors: sathyaprakash c. Stem Cell Reports. 2020 May 12;14(5):892-908. doi: 10.1016/j.stemcr.2020.03.023. Epub 2020 Apr 23. Stem Cell Reports. 2020. PMID: 32330447 Free PMC article.
Fine Tuning of Phosphorothioate Inclusion in 2'-O-Methyl Oligonucleotides Contributes to Specific Cell Targeting for Splice-Switching Modulation.
Aoki Y, Rocha CSJ, Lehto T, Miyatake S, Johansson H, Hashimoto Y, Nordin JZ, Mager I, Aoki M, Graham M, Sathyaprakash C, Roberts TC, Wood MJA, Behlke MA, Andaloussi SE. Aoki Y, et al. Among authors: sathyaprakash c. Front Physiol. 2021 Oct 13;12:689179. doi: 10.3389/fphys.2021.689179. eCollection 2021. Front Physiol. 2021. PMID: 34721051 Free PMC article.
C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia.
Aoki Y, Manzano R, Lee Y, Dafinca R, Aoki M, Douglas AGL, Varela MA, Sathyaprakash C, Scaber J, Barbagallo P, Vader P, Mäger I, Ezzat K, Turner MR, Ito N, Gasco S, Ohbayashi N, El Andaloussi S, Takeda S, Fukuda M, Talbot K, Wood MJA. Aoki Y, et al. Among authors: sathyaprakash c. Brain. 2017 Apr 1;140(4):887-897. doi: 10.1093/brain/awx024. Brain. 2017. PMID: 28334866