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Page 1
Dose-limiting inhibition of acetylcholinesterase by ladostigil results from the rapid formation and fast hydrolysis of the drug-enzyme complex formed by its major metabolite, R-MCPAI.
Moradov D, Finkin-Groner E, Bejar C, Sunita P, Schorer-Apelbaum D, Barasch D, Nemirovski A, Cohen M, Weinstock M. Moradov D, et al. Among authors: schorer apelbaum d. Biochem Pharmacol. 2015 Mar 15;94(2):164-72. doi: 10.1016/j.bcp.2015.01.017. Epub 2015 Feb 7. Biochem Pharmacol. 2015. PMID: 25662585
Synthesis and in vitro evaluation of anti-inflammatory activity of ester and amine derivatives of indoline in RAW 264.7 and peritoneal macrophages.
Furman S, Nissim-Bardugo E, Zeeli S, Weitman M, Nudelman A, Finkin-Groner E, Moradov D, Shifrin H, Schorer-Apelbaum D, Weinstock M. Furman S, et al. Among authors: schorer apelbaum d. Bioorg Med Chem Lett. 2014 May 15;24(10):2283-7. doi: 10.1016/j.bmcl.2014.03.081. Epub 2014 Apr 2. Bioorg Med Chem Lett. 2014. PMID: 24731278
Effect of chronic treatment with ladostigil (TV-3326) on anxiogenic and depressive-like behaviour and on activity of the hypothalamic-pituitary-adrenal axis in male and female prenatally stressed rats.
Poltyrev T, Gorodetsky E, Bejar C, Schorer-Apelbaum D, Weinstock M. Poltyrev T, et al. Among authors: schorer apelbaum d. Psychopharmacology (Berl). 2005 Aug;181(1):118-25. doi: 10.1007/s00213-005-2229-z. Epub 2005 Oct 15. Psychopharmacology (Berl). 2005. PMID: 15830235
15 results