Sweeny DJ[au] - Search Results

Year	Number of Results
1985	1
1986	1
1987	5
1988	3
1990	2
1991	1
1992	2
1995	1
1999	1
2000	1
2009	1
2010	2
2013	1
2022	1
2023	1
2024	0

1

Structure activity relationships leading to the identification of the indirect activator of AMPK, R419.

Shaw SJ, Goff DA, Carroll DC, Singh R, Sweeny DJ, Park G, Jenkins Y, Markovtsov V, Sun TQ, Issakani SD, Hitoshi Y, Payan DG. Shaw SJ, et al. Among authors: sweeny dj. Bioorg Med Chem. 2022 Oct 1;71:116951. doi: 10.1016/j.bmc.2022.116951. Epub 2022 Aug 1. Bioorg Med Chem. 2022. PMID: 35973281

2

Optimization of Pharmacokinetic and In Vitro Safety Profile of a Series of Pyridine Diamide Indirect AMPK Activators.

Shaw SJ, Goff DA, Boralsky LA, Singh R, Sweeny DJ, Park G, Sun TQ, Jenkins Y, Markovtsov V, Issakani SD, Payan DG, Hitoshi Y. Shaw SJ, et al. Among authors: sweeny dj. J Med Chem. 2023 Dec 28;66(24):17086-17104. doi: 10.1021/acs.jmedchem.3c01983. Epub 2023 Dec 11. J Med Chem. 2023. PMID: 38079537

3

Formation of conjugates of 2-fluoro-beta-alanine and bile acids during the metabolism of 5-fluorouracil and 5-fluoro-2-deoxyuridine in the isolated perfused rat liver.

Sweeny DJ, Barnes S, Diasio RB. Sweeny DJ, et al. Cancer Res. 1988 Apr 15;48(8):2010-4. Cancer Res. 1988. PMID: 2964897

4

N-chenodeoxycholyl-2-fluoro-beta-alanine: a biliary metabolite of 5-fluorouracil in humans.

Sweeny DJ, Martin M, Diasio RB. Sweeny DJ, et al. Drug Metab Dispos. 1988 Nov-Dec;16(6):892-4. Drug Metab Dispos. 1988. PMID: 2907471 No abstract available.

5

AMPK activation through mitochondrial regulation results in increased substrate oxidation and improved metabolic parameters in models of diabetes.

Jenkins Y, Sun TQ, Markovtsov V, Foretz M, Li W, Nguyen H, Li Y, Pan A, Uy G, Gross L, Baltgalvis K, Yung SL, Gururaja T, Kinoshita T, Owyang A, Smith IJ, McCaughey K, White K, Godinez G, Alcantara R, Choy C, Ren H, Basile R, Sweeny DJ, Xu X, Issakani SD, Carroll DC, Goff DA, Shaw SJ, Singh R, Boros LG, Laplante MA, Marcotte B, Kohen R, Viollet B, Marette A, Payan DG, Kinsella TM, Hitoshi Y. Jenkins Y, et al. Among authors: sweeny dj. PLoS One. 2013 Dec 5;8(12):e81870. doi: 10.1371/journal.pone.0081870. eCollection 2013. PLoS One. 2013. PMID: 24339975 Free PMC article.

6

Contribution of gut bacteria to the metabolism of the spleen tyrosine kinase (Syk) inhibitor R406 in cynomolgus monkey.

Sweeny DJ, Li W, Grossbard E, Lau DT. Sweeny DJ, et al. Xenobiotica. 2010 Jun;40(6):415-23. doi: 10.3109/00498251003734244. Xenobiotica. 2010. PMID: 20415544

7

Biological properties of the 2-fluoro-beta-alanine conjugates of cholic acid and chenodeoxycholic acid in the isolated perfused rat liver.

Sweeny DJ, Daher G, Barnes S, Diasio RB. Sweeny DJ, et al. Biochim Biophys Acta. 1990 Aug 13;1054(1):21-5. doi: 10.1016/0167-4889(90)90200-w. Biochim Biophys Acta. 1990. PMID: 2116908

8

Stereospecific synthesis of a GS 4104 metabolite: determination of absolute stereochemistry and influenza neuraminidase inhibitory activity.

Lew W, Escarpe PA, Mendel DB, Sweeny DJ, Kim CU. Lew W, et al. Among authors: sweeny dj. Bioorg Med Chem Lett. 1999 Oct 4;9(19):2811-4. doi: 10.1016/s0960-894x(99)00479-5. Bioorg Med Chem Lett. 1999. PMID: 10522696

9

Single- and multiple-dose disposition kinetics of sunitinib malate, a multitargeted receptor tyrosine kinase inhibitor: comparative plasma kinetics in non-clinical species.

Haznedar JO, Patyna S, Bello CL, Peng GW, Speed W, Yu X, Zhang Q, Sukbuntherng J, Sweeny DJ, Antonian L, Wu EY. Haznedar JO, et al. Among authors: sweeny dj. Cancer Chemother Pharmacol. 2009 Sep;64(4):691-706. doi: 10.1007/s00280-008-0917-1. Epub 2009 Jan 25. Cancer Chemother Pharmacol. 2009. PMID: 19169880

10

Metabolism of acetaminophen in hepatocytes isolated from mice and rats of various ages.

Sweeny DJ, Weiner M. Sweeny DJ, et al. Drug Metab Dispos. 1985 May-Jun;13(3):377-9. Drug Metab Dispos. 1985. PMID: 2862001 No abstract available.

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