Vallgårda J[au] - Search Results

Year	Number of Results
1991	2
1993	1
1996	1
2002	1
2006	1
2010	1
2024	0

1

Neuromedicinal chemistry of 5-HT1A-receptor agonists and antagonists.

Hacksell U, Liu Y, Yu H, Vallgårda J, Höök BB, Johansson AM, Lewander T. Hacksell U, et al. Among authors: vallgarda j. Drug Des Discov. 1993;9(3-4):287-97. Drug Des Discov. 1993. PMID: 8400009 Review.

2

trans-2-Aryl-N,N-dipropylcyclopropylamines: synthesis and interactions with 5-HT(1A) receptors.

Vallgårda J, Appelberg U, Arvidsson LE, Hjorth S, Svensson BE, Hacksell U. Vallgårda J, et al. J Med Chem. 1996 Mar 29;39(7):1485-93. doi: 10.1021/jm9507136. J Med Chem. 1996. PMID: 8691479

3

Active site variability of type 1 11beta-hydroxysteroid dehydrogenase revealed by selective inhibitors and cross-species comparisons.

Hult M, Shafqat N, Elleby B, Mitschke D, Svensson S, Forsgren M, Barf T, Vallgårda J, Abrahmsen L, Oppermann U. Hult M, et al. Among authors: vallgarda j. Mol Cell Endocrinol. 2006 Mar 27;248(1-2):26-33. doi: 10.1016/j.mce.2005.11.043. Epub 2006 Jan 20. Mol Cell Endocrinol. 2006. PMID: 16431016

4

Discovery of a potent, orally active 11beta-hydroxysteroid dehydrogenase type 1 inhibitor for clinical study: identification of (S)-2-((1S,2S,4R)-bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one (AMG 221).

Véniant MM, Hale C, Hungate RW, Gahm K, Emery MG, Jona J, Joseph S, Adams J, Hague A, Moniz G, Zhang J, Bartberger MD, Li V, Syed R, Jordan S, Komorowski R, Chen MM, Cupples R, Kim KW, St Jean DJ Jr, Johansson L, Henriksson MA, Williams M, Vallgårda J, Fotsch C, Wang M. Véniant MM, et al. Among authors: vallgarda j. J Med Chem. 2010 Jun 10;53(11):4481-7. doi: 10.1021/jm100242d. J Med Chem. 2010. PMID: 20465278

5

Intrinsic activity of enantiomers of 8-hydroxy-2-(di-n-propylamino)tetralin and its analogs at 5-hydroxytryptamine1A receptors that are negatively coupled to adenylate cyclase.

Cornfield LJ, Lambert G, Arvidsson LE, Mellin C, Vallgårda J, Hacksell U, Nelson DL. Cornfield LJ, et al. Among authors: vallgarda j. Mol Pharmacol. 1991 Jun;39(6):780-7. Mol Pharmacol. 1991. PMID: 1828859

6

A 3-D model for 5-HT1A-receptor agonists based on stereoselective methyl-substituted and conformationally restricted analogues of 8-hydroxy-2-(dipropylamino)tetralin.

Mellin C, Vallgårda J, Nelson DL, Björk L, Yu H, Andén NE, Csöregh I, Arvidsson LE, Hacksell U. Mellin C, et al. Among authors: vallgarda j. J Med Chem. 1991 Feb;34(2):497-510. doi: 10.1021/jm00106a004. J Med Chem. 1991. PMID: 1995871

7

Arylsulfonamidothiazoles as a new class of potential antidiabetic drugs. Discovery of potent and selective inhibitors of the 11beta-hydroxysteroid dehydrogenase type 1.

Barf T, Vallgårda J, Emond R, Häggström C, Kurz G, Nygren A, Larwood V, Mosialou E, Axelsson K, Olsson R, Engblom L, Edling N, Rönquist-Nii Y, Ohman B, Alberts P, Abrahmsén L. Barf T, et al. Among authors: vallgarda j. J Med Chem. 2002 Aug 29;45(18):3813-5. doi: 10.1021/jm025530f. J Med Chem. 2002. PMID: 12190302

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