In situ hybridization histochemistry (ISHH) was used to study the distribution of various 5-HT
1 receptor messenger RNAs (mRNA) in the mammalian nervous system. Since the cDNAs …

Introduction Hormonal receptors are of major importance in regula-tory physiological processes,
and major efforts have been dedicated to their pharmacological characterization. The …

The regional distribution and the pharmacology of the binding sites labelled with the novel 5-hydroxytryptamine
(serotonin) 5-HT 1B/1D selective radioligand serotonin-O-carboxy-methyl…

On his canvas entitled ‘La trahison des Images’(‘The Perfidy of Images’), Rent! Magritte painted
a tobacco pipe in a very realistic manner and added the words:‘Ceci n’est pas une pipe’(‘…

Graphics computer-generated three-dimensional models of all G-binding protein-coupled
receptors were built and analyzed. These models were defined using primary sequence …

The clinical utility and medico–economic value of several personalized diagnostic tests has
been well described in the literature. Development of such tests, including generation of the …

The neuronal protein 14‐3‐3 η is a candidate gene for schizophrenia because it maps
chromosome 22q12, a region implicated in the disease by linkage analysis, and is involved in …

Dopamine D 4 receptor antagonists are being developed by several pharmaceutical companies
as putative novel antipsychotics, possibly with low propensity to side‐effects. Two such …

Radioligand binding studies were performed in membranes of calf caudate, guinea-pig
cortex, dog caudate and whole brain, monkey caudate and whole brain, and human caudate …

In the present experiments we investigated endothelin (ET) receptors in the human coronary
artery, and in ventricular and atrial muscle using quantitative receptor autoradiography. …