Amino acid neurotransmitters and their pathways in the mammalian central nervous system

GE Fagg, AC Foster - Neuroscience, 1983 - Elsevier
The concept that amino acids might function as ne~ rotrausmitters in the central nervous
system (CNS) arose largely during the 1960s through the pioneering studies of Curtis, Krnjevii; …

Expert consensus document: Clinical and molecular diagnosis, screening and management of Beckwith-Wiedemann syndrome: an international consensus statement …

F Brioude, JM Kalish, A Mussa, AC Foster… - Nat Rev …, 2018 - openaccess.sgul.ac.uk
Beckwith-Wiedemann syndrome (BWS), a human genomic imprinting disorder, is characterized
by phenotypic variability that might include overgrowth, macroglossia, abdominal wall …

Glutamate-and GABA-based CNS therapeutics

AC Foster, JA Kemp - Current opinion in pharmacology, 2006 - Elsevier
Glutamate- and GABA-releasing neurons form the basis for neurotransmission in the
mammalian central nervous system (CNS). The co-ordination of these excitatory and inhibitory …

7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex.

JA Kemp, AC Foster, PD Leeson… - Proceedings of the …, 1988 - National Acad Sciences
Glycine markedly potentiates N-methyl-D-aspartate (N-Me-D-Asp) responses in mammalian
neurons by an action at a modulatory site on the N-Me-D-Asp receptor-ionophore complex. …

Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil

R Gill, AC Foster, GN Woodruff - Journal of Neuroscience, 1987 - Soc Neuroscience
… A preliminary account of some of this work has appeared in abstract form (Foster et al., …
degeneration can be evaluated in individual animals quite accurately using the method described …

Kynurenic acid blocks neurotoxicity and seizures induced in rats by the related brain metabolite quinolinic acid

AC Foster, A Vezzani, ED French, R Schwarcz - Neuroscience letters, 1984 - Elsevier
Kynurenic acid (KYNA) was tested as an antagonist of the neurotoxic and epileptogenic
effects of the metabolically related brain constituent quinolinic acid (QUIN). In the rat striatum, …

Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions

…, LR Watkins, GS Naeve, AC Foster - European Journal of …, 2004 - Wiley Online Library
Fractalkine is a unique chemokine reported to be constitutively expressed by neurons. Its
only receptor, CX3CR1, is expressed by microglia. Little is known about the expression of …

Gene expression analyses reveal molecular relationships among 20 regions of the human CNS

…, P Hevezi, J Lee, D Willhite, SM Lechner, AC Foster… - neurogenetics, 2006 - Springer
Transcriptional profiling was performed to survey the global expression patterns of 20
anatomically distinct sites of the human central nervous system (CNS). Forty-five non-CNS tissues …

Inhibition of TNF-alpha expression by adenosine: role of A3 adenosine receptors.

FG Sajjadi, K Takabayashi, AC Foster… - … (Baltimore, Md.: 1950 …, 1996 - journals.aai.org
… used to support that contention (2-CAdo) actually has greater affinity for AI and A3 than the
… production, it also can bind to A3 (AC Foster, unpublished data) and was less effective than I…

II. Excitotoxic models for neurodegenerative disorders

R Schwarcz, AC Foster, ED French, WO Whetsell Jr… - Life sciences, 1984 - Elsevier
In recent years, considerable interest has been shown in the neurotoxic properties of
excitatory amino acids and their possible relevance for the study of human neurodegenerative …