The fat-derived hormone leptin regulates energy balance in part by modulating the activity of
neuropeptide Y and proopiomelanocortin neurons in the hypothalamic arcuate nucleus. To …

The melanocortin-4 receptor (MC4-R) is an important regulator of energy homeostasis, and
evidence suggests that MC4-R-expressing neurons are downstream targets of leptin action. …

NPY and αMSH are expressed in distinct neurons in the arcuate nucleus of the hypothalamus,
where αMSH decreases and NPY increases food intake and body weight. Here we use …

The melanocortin system of the hypothalamus, including the neuropeptides α-melanocyte
stimulating hormone (αMSH) and agouti-related protein (AgRP), and their receptors, the …

▪ Abstract Multiple mechanisms exist to control the signaling and density of G-protein-coupled
receptors (GPRs). Upon agonist binding and receptor activation, a series of reactions …

Memory of a recently eaten meal can serve as a powerful mechanism for controlling future
eating behavior because it provides a record of intake that likely outlasts most physiological …

An increasing number of studies indicate that leptin can regulate the activity of the mesolimbic
dopamine system. The objective of this study was to examine the regulation of the activity …

… Address for reprint requests and other correspondence: AG Roseberry, Dept. of Biology,
Georgia State Univ., 24 Peachtree Center Ave., Suite 430SA, Atlanta, GA 30303 (e-mail: [email …

… Address for reprint requests and other correspondence: AG Roseberry, Dept. of Biology,
Georgia State Univ., 24 Peachtree Center Ave NE; Suite 430SA, Atlanta, GA 30303 (e-mail: […

… Similar to what we have observed previously (Roseberry 2013), MTII also dose dependently
decreased 24-h food intake (Fig. 2c; F(3,18) = 42.579, p < 0.001). Furthermore, because the …