A strategy for the synthesis of optically active ring-A methoxylated indole alkaloids which
employs the Moody azide/Schollkopf chiral auxiliary protocol has resulted in the successful …

… La Loggia, … in X0%, yield [>YY%ee, mp 14Y-151 “C, la]D?h -36.20’ (c=l. MeOH)]. ?I
The optical purity of 6 was established by comparison of its physical properties with those …

The synthesis and affinities of six new 3-substituted/3-carbolines (6-10, 12) for the
benzodiazepine receptor (BzR) are described. These analogs were used both to probe the …

Introduction Since the introduction of Librium in I9601 andthe subsequent discovery in 1977*
12-3 4567** of its mode of action via the-aminobutyric acid (GABA)/benzodiazepine …

Multidrug resistance (MDR) in neoplastic cells is usually due to decreased cellular retention
of drugs such as vincristine or doxorubicin. An ATP-dependent drug efflux pump has been …

… kis the volume of the k-th storage tank having area Aj … & La Loggia, G. 2009 Implementation
of a numerical model for the evaluation of potential apparent losses in a distribution network…

… La gestion des eaux côtières et des lagunes par les … la détermination du frottement dû à
la végétation immergée. Une plante typique des fonds côtiers sableux en Méditerranée est la …

A regio-and stereoselective functionalization methodology of linear dicarboxylic acids has
been developed and applied in the synthesis of paraconic acid natural products. Using this …

Social competence—defined as the ability to optimize social behaviour according to available
social information—can be influenced by the social environment experienced in early life. …

Climate change resulting from the enhanced greenhouse effect is expected to have significant
implications for the hydrological cycle. Several studies have pointed out the importance of …