User profiles for A. K. Pullikuth

Ashok K. Pullikuth

Wake Forest University School of Medicine
Verified email at wakehealth.edu
Cited by 2127

Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective

AK Pullikuth, AD Catling - Cellular signalling, 2007 - Elsevier
Cell migration is critical for many physiological processes and is often misregulated in
developmental disorders and pathological conditions including cancer and neurodegeneration. …

[HTML][HTML] Heliothis virescens and Manduca sextaLipid Rafts Are Involved in Cry1A Toxin Binding to the Midgut Epithelium and Subsequent Pore Formation

M Zhuang, DI Oltean, I Gómez, AK Pullikuth… - Journal of Biological …, 2002 - ASBMB
Lipid rafts are characterized by their insolubility in nonionic detergents such as Triton X-100
at 4 C. They have been studied in mammals, where they play critical roles in protein sorting …

ISG15 disrupts cytoskeletal architecture and promotes motility in human breast cancer cells

…, J Burks, LM Wood, AK Pullikuth… - Experimental …, 2012 - journals.sagepub.com
The interferon-stimulated gene 15 (ISG15) pathway is highly elevated in breast cancer;
however, very little is known about how the ISG15 pathway contributes to breast tumorigenesis. …

Dissecting intratumoral myeloid cell plasticity by single cell RNA‐seq

…, L Wudel, PC Chou, E Forbes, AK Pullikuth… - Cancer …, 2019 - Wiley Online Library
Tumor‐infiltrating myeloid cells are the most abundant leukocyte population within tumors.
Molecular cues from the tumor microenvironment promote the differentiation of immature …

Trk activation of the ERK1/2 kinase pathway stimulates intermediate chain phosphorylation and recruits cytoplasmic dynein to signaling endosomes for retrograde …

…, ED Jeffery, MW Ross, AK Pullikuth… - Journal of …, 2012 - Soc Neuroscience
… Escherichia coli Rosetta (DE3) pLysS (Novagen) expressing rat IC-2C in pET 21a were
grown, and IC-2C was purified as described previously (AK Pullikuth and AD Catling, …

Phylogeny and cloning of ion transporters in mosquitoes

AK Pullikuth, V Filippov, SS Gill - Journal of experimental …, 2003 - journals.biologists.com
… and its analogs (AK Pullikuth, K. Aimanova, W. Kang'ethe and SS Gill, unpublished). … studies
to ratify this prediction (AK Pullikuth, K. Aimanova, W. Kang'ethe and SS Gill, unpublished). …

Molecular characterization of sodium/proton exchanger 3 (NHE3) from the yellow fever vector, Aedes aegypti

AK Pullikuth, K Aimanova… - Journal of …, 2006 - journals.biologists.com
Transport across insect epithelia is thought to depend on the activity of a vacuolar-type
proton ATPase (V-ATPase) that energizes ion transport through a secondary proton/cation …

[HTML][HTML] Single-cell sequencing reveals the landscape of the human brain metastatic microenvironment

…, F Xing, HW Lo, L Craddock, AK Pullikuth… - Communications …, 2023 - nature.com
Brain metastases is the most common intracranial tumor and account for approximately 20%
of all systematic cancer cases. It is a leading cause of death in advanced-stage cancer, …

[HTML][HTML] Bulk and single-cell profiling of breast tumors identifies TREM-1 as a dominant immune suppressive marker associated with poor outcomes

AK Pullikuth, ED Routh, KD Zimmerman… - Frontiers in …, 2021 - frontiersin.org
Background Triggering receptor expressed on myeloid cells (TREM)-1 is a key mediator of
innate immunity previously associated with the severity of inflammatory disorders, and more …

Extracellular signal-regulated kinase promotes Rho-dependent focal adhesion formation by suppressing p190A RhoGAP

AK Pullikuth, AD Catling - Molecular and cellular biology, 2010 - Am Soc Microbiol
Cell migration is critical for normal development and for pathological processes including
cancer cell metastasis. Dynamic remodeling of focal adhesions and the actin cytoskeleton are …