User profiles for A. Elorza
Alvaro A. ElorzaFull Professor, Institute of Biomedical Sciences, Universidad Andres Bello Verified email at unab.cl Cited by 6389 |
Molecularly imprinted polymers: synthesis and characterisation
PAG Cormack, AZ Elorza - Journal of chromatography B, 2004 - Elsevier
This short review aims to present, in clear English, a summary of the principal synthetic
considerations pertaining to good practice in the polymerisation aspects of molecular imprinting, …
considerations pertaining to good practice in the polymerisation aspects of molecular imprinting, …
[HTML][HTML] Role of copper on mitochondrial function and metabolism
Copper is essential for life processes like energy metabolism, reactive oxygen species
detoxification, iron uptake, and signaling in eukaryotic organisms. Mitochondria gather copper for …
detoxification, iron uptake, and signaling in eukaryotic organisms. Mitochondria gather copper for …
[HTML][HTML] Role of oxidative stress as key regulator of muscle wasting during cachexia
Skeletal muscle atrophy is a pathological condition mainly characterized by a loss of muscular
mass and the contractile capacity of the skeletal muscle as a consequence of muscular …
mass and the contractile capacity of the skeletal muscle as a consequence of muscular …
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
Accumulation of depolarized mitochondria within β‐cells has been associated with oxidative
damage and development of diabetes. To determine the source and fate of depolarized …
damage and development of diabetes. To determine the source and fate of depolarized …
[HTML][HTML] High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria
Recently developed technologies have enabled multi-well measurement of O 2 consumption,
facilitating the rate of mitochondrial research, particularly regarding the mechanism of …
facilitating the rate of mitochondrial research, particularly regarding the mechanism of …
Mitochondrial networking protects β-cells from nutrient-induced apoptosis
…, JD Wikstrom, L Stiles, G Las, H Mohamed, A Elorza… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Previous studies have reported that β-cell mitochondria exist as discrete organelles
that exhibit heterogeneous bioenergetic capacity. To date, networking activity, and its …
that exhibit heterogeneous bioenergetic capacity. To date, networking activity, and its …
[PDF][PDF] Induction of the mitochondrial NDUFA4L2 protein by HIF-1α decreases oxygen consumption by inhibiting Complex I activity
…, E Balsa, B Acosta-Iborra, E Fuertes-Yebra, A Elorza… - Cell metabolism, 2011 - cell.com
The fine regulation of mitochondrial function has proved to be an essential metabolic adaptation
to fluctuations in oxygen availability. During hypoxia, cells activate an anaerobic switch …
to fluctuations in oxygen availability. During hypoxia, cells activate an anaerobic switch …
[PDF][PDF] HIF2α acts as an mTORC1 activator through the amino acid carrier SLC7A5
A Elorza, I Soro-Arnáiz, F Meléndez-Rodríguez… - Molecular cell, 2012 - cell.com
The mammalian target of rapamycin (mTOR) pathway, which is essential for cell proliferation,
is repressed in certain cell types in hypoxia. However, hypoxia-inducible factor 2α (HIF2α) …
is repressed in certain cell types in hypoxia. However, hypoxia-inducible factor 2α (HIF2α) …
Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing
…, H Anta, M Santos-Galindo, V Swarup, A Elorza… - Nature, 2018 - nature.com
Common genetic contributions to autism spectrum disorder (ASD) reside in risk gene
variants that individually have minimal effect sizes. As environmental factors that perturb …
variants that individually have minimal effect sizes. As environmental factors that perturb …
[HTML][HTML] β‐arrestin‐and c‐Src‐dependent degradation of G‐protein‐coupled receptor kinase 2
P Penela, A Elorza, S Sarnago, F MayorJr - The EMBO journal, 2001 - embopress.org
G‐protein‐coupled receptor kinase 2 (GRK2) plays a key role in the regulation of G‐protein‐coupled
receptors (GPCRs). GRK2 expression is altered in several pathological conditions, …
receptors (GPCRs). GRK2 expression is altered in several pathological conditions, …