The bone replacement process in the adult skeleton is known as remodeling. When bone is
removed by osteoclasts, new bone is laid down by osteoblasts in the same place, because …

The state of vitamin D nutrition depends on synthesis in the skin under the influence of sunlight
as well as on dietary intake. In European countries that do not fortify milk with vitamin D, …

Most discussions of bone remodeling focus on how it is influenced by hormones, cytokines,
growth factors, and other molecules, and pay no attention to why it occurs. All physiologic …

P with each other in a variety of arcane languages, which in general are unintelligible to
those outside the field. Many in the bone and mineral scientific community would like to keep …

We devised a new method for examining the structural changes that occur in trabecular bone
in aging and in osteoporosis. With simultaneous measurement of total perimeter and bone …

Glucocorticoid-induced bone disease is characterized by decreased bone formation and in
situ death of isolated segments of bone (osteonecrosis) suggesting that glucocorticoid excess…

The mass of regenerating tissues, such as bone, is critically dependent on the number of
executive cells, which in turn is determined by the rate of replication of progenitors and the life-…

We compared indices of three-dimensional microstructure of iliac trabecular bone between
26 patients with vertebral compression fractures due to postmenopausal osteoporosis and 24 …

Glucocorticoid-induced osteoporosis may be due, in part, to increased apoptosis of osteocytes
and osteoblasts, and bisphosphonates (BPs) are effective in the management of this …

Both aging and loss of sex steroids have adverse effects on skeletal homeostasis, but whether
and how they may influence each others negative impact on bone remains unknown. We …