Bone mineral density in patients with cervical and trochanteric fractures of the proximal femur

…, H Gomez, A Garrido, L Melo, AO Sahores - Osteoporosis …, 1991 - Springer
The bone mineral density (BMD) of the proximal femur, spine and radius shaft was determined
in 75 women with atraumatic fractures of the proximal femur (FXf) (average age: 70.1±9.6 …

Enhanced antitumor immunity via endocrine therapy prevents mammary tumor relapse and increases immune checkpoint blockade sensitivity

GR Sequeira, A Sahores, T Dalotto-Moreno… - Cancer research, 2021 - AACR
Antiprogestin therapy induces immunogenic tumor cell death in PRA-overexpressing tumors,
eliciting an adaptive immune memory response that protects mice from future tumor …

MRP4/ABCC4 as a new therapeutic target: meta-analysis to determine cAMP binding sites as a tool for drug design

A Yaneff, A Sahores, N Gómez… - Current Medicinal …, 2019 - ingentaconnect.com
MRP4 transports multiple endogenous and exogenous substances and is critical not only for
detoxification but also in the homeostasis of several signaling molecules. Its dysregulation …

Targeting FGFR with BGJ398 in breast cancer: effect on tumor growth and metastasis

A Sahores, M May, GR Sequeira… - Current cancer drug …, 2018 - ingentaconnect.com
Background: Endocrine resistance and metastatic dissemination comprise major clinical
challenges for breast cancer treatment. The fibroblast growth factor receptor family (FGFR) …

Identification of MRP4/ABCC4 as a target for reducing the proliferation of pancreatic ductal adenocarcinoma cells by modulating the cAMP efflux

…, A Yaneff, N Gomez, N Di Siervi, A Sahores… - Molecular …, 2019 - ASPET
Pancreatic cancer is one of the most lethal types of tumors with no effective therapy available;
is currently the third leading cause of cancer in developed countries; and is predicted to …

Involvement of histamine H1 and H2 receptor inverse agonists in receptor's crossregulation

…, CD Zappia, AR González, A Sahores… - European Journal of …, 2019 - Elsevier
Histamine [2-(4-Imidazolyl)-ethylamine] modulates different biological processes, through
histamine H 1 and H 2 receptors, and their respective blockers are widely used in treating …

FGFR3 down-regulation is involved in bacillus Calmette-Guérin induced bladder tumor growth inhibition

…, B Prack McCormick, A Sahores… - The Journal of …, 2016 - auajournals.org
Purpose : Bacillus Calmette-Guérin is the standard treatment for patients with nonmuscle
invasive high histological grade bladder cancer. Previously we found that bacillus Calmette-…

[HTML][HTML] Increased high molecular weight FGF2 in endocrine-resistant breast cancer

A Sahores, V Figueroa, M May, M Liguori… - Hormones and …, 2018 - Springer
Endocrine resistance may develop as a consequence of enhanced growth factor signaling.
Fibroblast growth factor 2 (FGF2) consists of a low and several high molecular weight forms (…

[HTML][HTML] Novel, low cost, highly effective, handmade steroid pellets for experimental studies

A Sahores, GM Luque, V Wargon, M May, A Molinolo… - PLoS …, 2013 - journals.plos.org
The basic component of Silastic® glue (Dow Corning) used to prepare Silastic® pellets is
polydimethylsiloxane. This compound is also present in other commercial adhesives such as …

[HTML][HTML] Multidrug transporter MRP4/ABCC4 as a key determinant of pancreatic cancer aggressiveness

A Sahores, A Carozzo, M May, N Gomez, N Di Siervi… - Scientific Reports, 2020 - nature.com
Recent findings show that MRP4 is critical for pancreatic ductal adenocarcinoma (PDAC) cell
proliferation. Nevertheless, the significance of MRP4 protein levels and function in PDAC …