A genetic interaction network containing ∼1000 genes and ∼4000 interactions was mapped
by crossing mutations in 132 different query genes into a set of ∼4700 viable gene yeast …

Glycosylation constitutes one of the most important of all the post-translational modifications
and may have numerous effects on the function, structure, physical properties and targeting …

The sequenced yeast genome offers a unique resource for the analysis of eukaryotic cell
function and enables genome-wide screens for genes involved in cellular processes. We have …

The genome of Saccharomyces cerevisiae contains five genes that encode type II transmembrane
proteins with significant amino acid similarity to the α-1,3-mannosyltransferase Mnn1p…

Background In S. cerevisiae the β-1,4-linked N-acetylglucosamine polymer, chitin, is synthesized
by a family of 3 specialized but interacting chitin synthases encoded by CHS1, CHS2 …

Large-scale screening of genetic and chemical-genetic interactions was used to examine
the assembly and regulation of β-1,3-glucan in Saccharomyces cerevisiae. Using the set of …

Using the set of Saccharomyces cerevisiae mutants individually deleted for 5718 yeast genes,
we screened for altered sensitivity to the antifungal protein, K1 killer toxin, that binds to a …

We have determined a role for Ktr1p and Ktr3p as mannosyltransferases in the synthesis of
the carbohydrate chains attached to Saccharomyces cerevisiae O- andN-modified proteins. …

The yeast Kre2p/Mnt1p alpha 1,2-mannosyltransferase is a type II membrane protein with a
short cytoplasmic amino terminus, a membrane-spanning region, and a large catalytic …

Eukaryotic glycan structures are progressively elaborated in the secretory pathway. Following
the addition of a core N-linked carbohydrate in the endoplasmic reticulum, glycoproteins …