User profiles for A. Speelman
Amy SpeelmanPacific Northwest National Laboratory Verified email at pnnl.gov Cited by 935 |
How might physical activity benefit patients with Parkinson disease?
AD Speelman, BP Van De Warrenburg… - Nature Reviews …, 2011 - nature.com
Parkinson disease (PD) is a neurodegenerative disorder characterized by progressive motor
and nonmotor impairments. These impairments incline many patients towards a sedentary …
and nonmotor impairments. These impairments incline many patients towards a sedentary …
Mono-and dinuclear non-heme iron–nitrosyl complexes: Models for key intermediates in bacterial nitric oxide reductases
TC Berto, AL Speelman, S Zheng, N Lehnert - Coordination Chemistry …, 2013 - Elsevier
High-spin non-heme iron–nitrosyls are of direct interest to both the chemical and biological
communities as these species exhibit interesting chemical properties and act as direct …
communities as these species exhibit interesting chemical properties and act as direct …
Nonpharmacologic treatment of chronic insomnia
This paper reviews the evidence regarding the efficacy of nonpharmacological treatments
for primary chronic insomnia. It is based on a review of 48 clinical trials and two meta-analyses …
for primary chronic insomnia. It is based on a review of 48 clinical trials and two meta-analyses …
[HTML][HTML] Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities
DI Draganov, JF Teiber, A Speelman, Y Osawa… - Journal of lipid …, 2005 - ASBMB
The paraoxonase (PON) gene family in humans has three members, PON1, PON2, and
PON3. Their physiological role(s) and natural substrates are uncertain. We developed a …
PON3. Their physiological role(s) and natural substrates are uncertain. We developed a …
[HTML][HTML] Physical inactivity in Parkinson's disease
M van Nimwegen, AD Speelman… - Journal of …, 2011 - Springer
Patients with Parkinson’s disease (PD) are likely to become physically inactive, because of
their motor, mental, and emotional symptoms. However, specific studies on physical activity …
their motor, mental, and emotional symptoms. However, specific studies on physical activity …
Promotion of physical activity and fitness in sedentary patients with Parkinson's disease: randomised controlled trial
M van Nimwegen, AD Speelman, S Overeem… - Bmj, 2013 - bmj.com
Objective To evaluate whether a multifaceted behavioural change programme increases
physical activities in patients with Parkinson’s disease. Design Multicentre randomised …
physical activities in patients with Parkinson’s disease. Design Multicentre randomised …
Treatment of chronic insomnia by restriction of time in bed
AJ Spielman, P Saskin, MJ Thorpy - Sleep, 1987 - academic.oup.com
A treatment of chronic insomnia is described that is based on the recognition that excessive
time spent in bed is one of the important factors that perpetuates insomnia. Thirty-five patients…
time spent in bed is one of the important factors that perpetuates insomnia. Thirty-five patients…
Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals
…, JD Malhotra, DP McEwen, A Speelman… - Journal of molecular and …, 2007 - Elsevier
In neurons, voltage-gated sodium channel β subunits regulate the expression levels, subcellular
localization, and electrophysiological properties of sodium channel α subunits. However…
localization, and electrophysiological properties of sodium channel α subunits. However…
Parkinson's disease and osteoporosis
F Van Den Bos, AD Speelman, M Samson… - Age and …, 2013 - academic.oup.com
Background: patients with Parkinson's disease (PD) have a high risk of sustaining
osteoporotic fractures as a result of falls and reduced bone mass. Objective: to summarise the …
osteoporotic fractures as a result of falls and reduced bone mass. Objective: to summarise the …
Duration of tick attachment and Borrelia burgdorferi transmission
…, TN Mather, RJ Sinsky, A Spielman - Journal of clinical …, 1987 - Am Soc Microbiol
Nymphal Ixodes dammini transmitted Borrelia burgdorferi to 1 of 14 rodents exposed for 24
h, 5 of 14 rodents exposed for 48 h, and 13 of 14 rodents exposed for greater than or equal to …
h, 5 of 14 rodents exposed for 48 h, and 13 of 14 rodents exposed for greater than or equal to …