User profiles for Adam Giangreco
Adam GiangrecoUniversity of the Highlands and Islands Verified email at uhi.ac.uk Cited by 5897 |
Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction
A Giangreco, SD Reynolds, BR Stripp - The American journal of pathology, 2002 - Elsevier
Cellular mechanisms contributing to renewal of terminal bronchioles remain poorly defined.
Our previous studies identified pollutant-resistant Clara cell secretory protein (CCSP)-…
Our previous studies identified pollutant-resistant Clara cell secretory protein (CCSP)-…
Clara cell secretory protein–expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial …
KU Hong, SD Reynolds, A Giangreco… - American journal of …, 2001 - atsjournals.org
Stem cells with potential to contribute to the re-establishment of the normal bronchiolar
epithelium have not been definitively demonstrated. We previously established that …
epithelium have not been definitively demonstrated. We previously established that …
[HTML][HTML] Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration
SD Reynolds, A Giangreco, JHT Power… - The American journal of …, 2000 - Elsevier
Remodeling of the conducting airway epithelium is a common finding in the chronically injured
lung and has been associated with increased risk for developing lung cancer. Pulmonary …
lung and has been associated with increased risk for developing lung cancer. Pulmonary …
Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis
The dermal papilla comprises the specialised mesenchymal cells at the base of the hair
follicle. Communication between dermal papilla cells and the overlying epithelium is essential …
follicle. Communication between dermal papilla cells and the overlying epithelium is essential …
Stem cells are dispensable for lung homeostasis but restore airways after injury
A Giangreco, EN Arwert, IR Rosewell… - Proceedings of the …, 2009 - National Acad Sciences
Local tissue stem cells have been described in airways of the lung but their contribution to
normal epithelial maintenance is currently unknown. We therefore developed aggregation …
normal epithelial maintenance is currently unknown. We therefore developed aggregation …
[PDF][PDF] β-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells
V Silva-Vargas, CL Celso, A Giangreco, T Ofstad… - Developmental cell, 2005 - cell.com
Using K14ΔNβ-cateninER transgenic mice, we show that short-term, low-level β-catenin
activation stimulates de novo hair follicle formation from sebaceous glands and interfollicular …
activation stimulates de novo hair follicle formation from sebaceous glands and interfollicular …
Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids
…, G Allen, R Butler, M Zilbauer, A Giangreco… - elife, 2017 - elifesciences.org
10.7554/eLife.26575.001 The embryonic mouse lung is a widely used substitute for human
lung development. For example, attempts to differentiate human pluripotent stem cells to lung …
lung development. For example, attempts to differentiate human pluripotent stem cells to lung …
Conditional clara cell ablation reveals a self-renewing progenitor function of pulmonary neuroendocrine cells
SD Reynolds, KU Hong, A Giangreco… - … of Physiology-Lung …, 2000 - journals.physiology.org
The neuroepithelial body (NEB) is a highly dynamic structure that responds to chronic airway
injury through hyperplasia of associated pulmonary neuroendocrine (PNE) cells. Although …
injury through hyperplasia of associated pulmonary neuroendocrine (PNE) cells. Although …
The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells
JGW Nijhof, KM Braun, A Giangreco, C van Pelt… - 2006 - journals.biologists.com
We describe a novel murine progenitor cell population localised to a previously uncharacterised
region between sebaceous glands and the hair follicle bulge, defined by its reactivity to …
region between sebaceous glands and the hair follicle bulge, defined by its reactivity to …
Epidermal stem cells are retained in vivo throughout skin aging
A Giangreco, M Qin, JE Pintar, FM Watt - Aging cell, 2008 - Wiley Online Library
In healthy individuals, skin integrity is maintained by epidermal stem cells which self‐renew
and generate daughter cells that undergo terminal differentiation. It is currently unknown …
and generate daughter cells that undergo terminal differentiation. It is currently unknown …