User profiles for Adolfo Borges
Adolfo BorgesCentro para el Desarrollo de la Investigación Científica Verified email at cedic.org.py Cited by 3349 |
Snake Venomics of the Central American Rattlesnake Crotalus simus and the South American Crotalus durissus Complex Points to Neurotoxicity as an Adaptive Paedomorphic …
…, M Flores-Diaz, MC Dos Santos, A Borges… - Journal of proteome …, 2010 - ACS Publications
We report a comparative venomic and antivenomic characterization of the venoms of
newborn and adult specimens of the Central American rattlesnake, Crotalus simus, and of the …
newborn and adult specimens of the Central American rattlesnake, Crotalus simus, and of the …
A common structural motif in thiamin pyrophosphate-binding enzymes
CF Hawkins, A Borges, RN Perham - FEBS letters, 1989 - Elsevier
The amino acid sequences of a wide range of enzymes that utilize thiamin pyrophosphate (TPP)
as cofactor have been compared. A common sequence motif approximately 30 residues …
as cofactor have been compared. A common sequence motif approximately 30 residues …
Snake population venomics and antivenomics of Bothrops atrox: Paedomorphism along its transamazonian dispersal and implications of geographic venom variability …
We describe two geographically differentiated venom phenotypes across the wide distribution
range of Bothrops atrox, from the Colombian Magdalena Medio Valley through Puerto …
range of Bothrops atrox, from the Colombian Magdalena Medio Valley through Puerto …
Snake venomics and antivenomics of Bothrops colombiensis, a medically important pitviper of the Bothrops atrox-asper complex endemic to Venezuela: Contributing …
JJ Calvete, A Borges, Á Segura, M Flores-Díaz… - Journal of …, 2009 - Elsevier
The taxonomic status of the medically important pitviper of the Bothrops atrox-asper complex
endemic to Venezuela, which has been classified as Bothrops colombiensis, remains …
endemic to Venezuela, which has been classified as Bothrops colombiensis, remains …
Subtype specificity of scorpion β-toxin Tz1 interaction with voltage-gated sodium channels is determined by the pore loop of domain 3
Voltage-gated sodium (Na v ) channels are modulated by a variety of specific neurotoxins.
Scorpion β-toxins affect the voltage-dependence of channel gating: In their presence, Na v …
Scorpion β-toxins affect the voltage-dependence of channel gating: In their presence, Na v …
Impact of Regional Variation in Bothrops asper Snake Venom on the Design of Antivenoms: Integrating Antivenomics and Neutralization Approaches
Intraspecific snake venom variations have implications in the preparation of venom pools for
the generation of antivenoms. The impact of such variation in the cross-reactivity of …
the generation of antivenoms. The impact of such variation in the cross-reactivity of …
µO-Conotoxins Inhibit NaV Channels by Interfering with their Voltage Sensors in Domain-2
The µO-conotoxins MrVIA and MrVIB are 31-residue peptides from Conus marmoreus,
belonging to the O-superfamily of conotoxins with three disulfide bridges. They have attracted …
belonging to the O-superfamily of conotoxins with three disulfide bridges. They have attracted …
Venom diversity in the Neotropical scorpion genus Tityus: Implications for antivenom design emerging from molecular and immunochemical analyses across endemic …
Scorpions of the Neotropical genus Tityus are responsible for most severe envenomations
in the Caribbean, South America, and Lower Central America (LCA). Although Tityus is …
in the Caribbean, South America, and Lower Central America (LCA). Although Tityus is …
Molecular systematics of the neotropical scorpion genus Tityus (Buthidae): the historical biogeography and venom antigenic diversity of toxic Venezuelan species
A Borges, E Bermingham, N Herrera, MJ Alfonzo… - Toxicon, 2010 - Elsevier
We provide a mitochondrial DNA-based phylogenetic hypothesis for 21 Tityus species
collected in Venezuela, Trinidad, Brazil and Panama, including 12 taxa known to be toxic to …
collected in Venezuela, Trinidad, Brazil and Panama, including 12 taxa known to be toxic to …
An overview of Tityus cisandinus scorpion venom: Transcriptome and mass fingerprinting reveal conserved toxin homologs across the Amazon region and novel …
Tityus cisandinus, a neglected medically important scorpion in Ecuadorian and Peruvian
Amazonia, belongs to a complex of species related to the eastern Amazon endemic Tityus …
Amazonia, belongs to a complex of species related to the eastern Amazon endemic Tityus …