Recent observations that several trans‐platinum complexes exhibit antitumor activity
including activity in cisplatin‐resistant tumor cells, violates the classical structure/activity …

We synthesized a novel platinum drug,cis-[PtCl(NH 3 ) 2 (N7-ACV)] + , in which ACV is the
antiviral drug acyclovir [a deoxyriboguanosine analogue, 9-(2-hydroxyethoxymethyl)guanine]. …

Modifications of natural DNA in a cell‐free medium by dinuclear bisplatinum complexes with
equivalent coordination spheres, represented by the general formula [{trans‐PtCl(NH 3 ) 2 } …

Background Exercise-associated hyponatremia (EAH), rhabdomyolysis and renal failure
appear to be a unique problem in ultra-endurance racers. Methods We investigated the …

Although moderate exercise is beneficial for the human body and its immune system, exhaustive
ultra-endurance performance in cold conditions might be harmful. The aim of this study …

Generally, rodents and other small mammals are considered as one of the sources of
Toxoplasma gondii or Neospora caninum infection for cats and dogs as the definitive hosts of …

Background To assess the prevalence of exercise-associated hyponatremia (EAH) in two 24-hour
mountain bike (MTB) (R1,R2), one 24-hour running (R3) and one multi-stage MTB (R4…

The ever‐increasing number of Lyme borreliosis patients led us to consider more effective
procedures for disease prevention. The aim of our study was to monitor the annual activity …

Ticks represent the primary vectors of several serious diseases, including the Lyme disease
caused by Borrelia burgdorferi sensu lato (Bbsl). In this study two dominant ectoparasitic …

A total of 305 ticks (21 larvae, 243 nymphs, 19 females and 22 males) were collected by
flagging of vegetation in suburban woods of Pisárky Park (city of Brno) from July to October 2002…