User profiles for Alexander Storch
Alexander StorchUniversity of Rostock Verified email at med.uni-rostock.de Cited by 19524 |
Efficient generation of neural stem cell-like cells from adult human bone marrow stromal cells
…, J Schwarz, R Brenner, A Storch - Journal of cell …, 2004 - journals.biologists.com
Clonogenic neural stem cells (NSCs) are self-renewing cells that maintain the capacity to
differentiate into brain-specific cell types, and may also replace or repair diseased brain tissue. …
differentiate into brain-specific cell types, and may also replace or repair diseased brain tissue. …
[PDF][PDF] Direct reprogramming of fibroblasts into neural stem cells by defined factors
…, JH Yang, HT Lee, JC Schwamborn, A Storch… - Cell stem cell, 2012 - cell.com
Recent studies have shown that defined sets of transcription factors can directly reprogram
differentiated somatic cells to a different differentiated cell type without passing through a …
differentiated somatic cells to a different differentiated cell type without passing through a …
Treadmill training for patients with Parkinson's disease
Background Treadmill training is used in rehabilitation and is described as improving gait
parameters of patients with Parkinson's disease. Objectives To assess the effectiveness of …
parameters of patients with Parkinson's disease. Objectives To assess the effectiveness of …
Nonmotor fluctuations in Parkinson disease: severity and correlation with motor complications
A Storch, CB Schneider, M Wolz, Y Stürwald, A Nebe… - Neurology, 2013 - AAN Enterprises
… Storch was responsible for study concept and design, acquisition of data, statistical analyses
and interpretation of data, chairing the NoMoFlu-PD steering committee, and drafting the …
and interpretation of data, chairing the NoMoFlu-PD steering committee, and drafting the …
A star-PEG–heparin hydrogel platform to aid cell replacement therapies for neurodegenerative diseases
…, W Panyanuwat, S Zschoche, D Meinhold, A Storch… - Biomaterials, 2009 - Elsevier
Biofunctional matrices for in vivo tissue engineering strategies must be modifiable in both
biomolecular composition and mechanical characteristics. To address this challenge, we …
biomolecular composition and mechanical characteristics. To address this challenge, we …
Long-term proliferation and dopaminergic differentiation of human mesencephalic neural precursor cells
We report on generation of dopamine neurons from long-term cultures of human fetal
mesencephalic precursor cells. These CNS precursor cells were successfully expanded in vitro …
mesencephalic precursor cells. These CNS precursor cells were successfully expanded in vitro …
Transcriptional Profiles of CD133+ and CD133− Glioblastoma-Derived Cancer Stem Cell Lines Suggest Different Cells of Origin
Glioblastoma multiforme (GBM) is paradigmatic for the investigation of cancer stem cells (CSC)
in solid tumors. Growing evidence suggests that different types of CSC lead to the …
in solid tumors. Growing evidence suggests that different types of CSC lead to the …
Increased susceptibility to sporadic Parkinson's disease by a certain combined α‐synuclein/apolipoprotein E genotype
Parkinson's disease (PD) is one of the most common neurodegenerative disorders affecting
about 1% of Western populations older than age 50. The pathological hallmark of PD are …
about 1% of Western populations older than age 50. The pathological hallmark of PD are …
Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease
Background Major hallmarks in the pathophysiology of Parkinson disease are cellular energy
depletion and oxidative stress leading to cellular dysfunction and death. Coenzyme Q 10 (…
depletion and oxidative stress leading to cellular dysfunction and death. Coenzyme Q 10 (…
[HTML][HTML] Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation
Amyotrophic lateral sclerosis (ALS) is the most frequent motor neuron disease. Cytoplasmic
fused in sarcoma (FUS) aggregates are pathological hallmarks of FUS-ALS. Proper shuttling …
fused in sarcoma (FUS) aggregates are pathological hallmarks of FUS-ALS. Proper shuttling …