ORKAMBI-mediated rescue of mucociliary clearance in cystic fibrosis primary respiratory cultures is enhanced by arginine uptake, arginase inhibition, and promotion …

YS Wu, J Jiang, S Ahmadi, A Lew, O Laselva… - Molecular …, 2019 - ASPET
ORKAMBI, a combination of the corrector, lumacaftor, and the potentiator, ivacaftor, partially
rescues the defective processing and anion channel activity conferred by the major cystic …

Augmentation of cystic fibrosis transmembrane conductance regulator function in human bronchial epithelial cells via SLC6A14-dependent amino acid uptake …

…, M Di Paola, K Du, S Xia, A Lew… - American journal of …, 2019 - atsjournals.org
SLC6A14-mediated l-arginine transport has been shown to augment the residual anion
channel activity of the major mutant, F508del-CFTR, in the murine gastrointestinal tract. It is not …

Protein Targeting of L1CAM Mutants in Cultured Neurons

G Raimondi, A Boering, S Pignatelli, C Lew… - 2017 - digitalcommons.sacredheart.edu
The correct targeting of proteins to axons and dendrites of neurons is essential for the proper
development of the nervous system. L1CAM is an axonally-targeted protein responsible for …

[BOOK][B] Regulation of CFTR function and stability by phosphorylation and its membrane environment

S Chin - 2019 - search.proquest.com
Cystic Fibrosis is caused by mutations of the gene that codes for Cystic Fibrosis Transmembrane
conductance Regulator (CFTR), an ATP-Binding Cassette anion channel. The major …

[HTML][HTML] An analysis of age-standardized suicide rates in Muslim-majority countries in 2000-2019

B Lew, D Lester, K Kõlves, PSF Yip, YY Chen… - BMC public health, 2022 - Springer
Background This study examines the 20-year trend of suicide in 46 Muslim-majority countries
throughout the world and compares their suicide rates and trends with the global average. …

A National Look at the High School Counseling Office: What Is It Doing and What Role Can It Play in Facilitating Students' Paths to College?.

AW Radford, N Ifill, T Lew - National Association for College Admission …, 2016 - ERIC
Between January and October of 2013, nearly 3 million Americans between the ages of 16
and 24 graduated from high school. By October of that year, just two-thirds had enrolled in …

PClean: Bayesian data cleaning at scale with domain-specific probabilistic programming

A Lew, M Agrawal, D Sontag… - … conference on artificial …, 2021 - proceedings.mlr.press
Data cleaning is naturally framed as probabilistic inference in a generative model of ground-truth
data and likely errors, but the diversity of real-world error patterns and the hardness of …

Before restriction became exclusion: America's experiment in diplomatic immigration control

B Lew-Williams - Pacific Historical Review, 2014 - online.ucpress.edu
The Chinese Exclusion Act (1882) marked a turning point in the history of US immigration
control, but it was not as definitive a move toward gatekeeping as historians have suggested. …

Ciprofloxacin versus trimethoprim/sulfamethoxazole for prophylaxis of bacterial infections in bone marrow transplant recipients: a randomized, controlled trial.

MA Lew, K Kehoe, J Ritz, KH Antman… - Journal of clinical …, 1995 - ascopubs.org
PURPOSE To compare the efficacy and safety of ciprofloxacin (CIP) and trimethoprim/sulfamethoxazole
(TMS) for the prevention of bacterial infections in patients who received bone …

Sketching a Theology of Song

L Lew - New blackfriars, 2013 - cambridge.org
… Building on Clement of Alexandria's image of Christ as the New Song, the analogy is further
developed to explore the theology of the new creation, in which the gracious work of the …