CTX, a Xenopus thymocyte receptor, defines a molecular family conserved throughout vertebrates

I Chrétien, A Marcuz, M Courtet… - European journal of …, 1998 - Wiley Online Library
CTX, a cortical thymocyte marker in Xenopus, is an immunoglobulin superfamily (Igsf)
member comprising one variable and one constant C2‐type Igsf domain, a transmembrane …

Evolutionary relationships of the Tas2r receptor gene families in mouse and human

C Conte, M Ebeling, A Marcuz, P Nef… - Physiological …, 2003 - journals.physiology.org
The early molecular events in the perception of bitter taste start with the binding of specific
water-soluble molecules to G protein-coupled receptors (GPCRs) encoded by the Tas2r family …

Mapping the binding pocket of dual antagonist almorexant to human orexin 1 and orexin 2 receptors: comparison with the selective OX1 antagonist SB-674042 and …

P Malherbe, O Roche, A Marcuz, C Kratzeisen… - Molecular …, 2010 - ASPET
The orexins and their receptors are involved in the regulation of arousal and sleep–wake
cycle. Clinical investigation with almorexant has indicated that this dual OX antagonist is …

Axolotl MHC architecture and polymorphism

…, P Ducoroy, V Laurens, A Marcuz… - European journal of …, 1999 - Wiley Online Library
The MHC of the urodele amphibian Ambystoma mexicanum consists of multiple polymorphic
class I loci linked, so far as yet known, to a single class II B locus. This architecture is very …

CTX, a novel molecule specifically expressed on the surface of cortical thymocytes in Xenopus

I Chrétien, J Robert, A Marcuz… - European journal of …, 1996 - Wiley Online Library
CTX, a novel developmentally regulated type‐I transmembrane protein is expressed
specifically by a large fraction of cortical thymocytes in the amphibian Xenopus. This apparently …

Membrane exon sequences of the three Xenopus Ig classes explain the evolutionary origin of mammalian isotypes

R Mußmann, M Wilson, A Marcuz… - European journal of …, 1996 - Wiley Online Library
We have cloned and sequenced the genes corresponding to the membrane exons of the
three immunoglobulin (Ig) heavy chain isotypes (μ, ν and χ) of Xenopus. Among membrane Ig (…

The T cell receptor β genes of Xenopus

I Chrétien, A Marcuz, J Fellah… - European journal of …, 1997 - Wiley Online Library
cDNA of the T cell receptor β (TCRB) have been isolated from the anuran amphibian Xenopus
and they show strong structural homology to TCRB sequences of other vertebrates. Ten …

Me-talnetant and osanetant interact within overlapping but not identical binding pockets in the human tachykinin neurokinin 3 receptor transmembrane domains

P Malherbe, C Bissantz, A Marcuz, C Kratzeisen… - Molecular …, 2008 - ASPET
Recent clinical trials have indicated that neurokinin 3 receptor antagonists (S)-(+)-N-{{3-[1-benzoyl-3-(3,4-dichlorophenyl)-piperidin-3-yl]prop-1-yl}-4-phenylpiperidin-4-yl}-N-…

Conservation of structural and functional domains in complement component C3 of Xenopus and mammals.

D Grossberger, A Marcuz… - Proceedings of the …, 1989 - National Acad Sciences
The cDNA sequence and the deduced amino acid sequence of the Mr 34,000 C-terminal
fragment of Xenopus laevis complement component C3 are presented. The sequence of …

The fate of duplicated major histocompatibility complex class Ia genes in a dodecaploid amphibian, Xenopus ruwenzoriensis

B Sammut, A Marcuz… - European journal of …, 2002 - Wiley Online Library
The dodecaploid anuran amphibian Xenopus ruwenzoriensis represents the only polyploid
species of Xenopus in which the full silencing of the extra copies of the major …