Steady‐state activation and modulation of the synaptic‐type α1β2γ2L GABAA receptor by combinations of physiological and clinical ligands

…, SR Pierce, TC Senneff, AB Burbridge… - Physiological …, 2019 - Wiley Online Library
The synaptic α1β2γ2 GABA A receptor is activated phasically by presynaptically released
GABA. The receptor is considered to be inactive between synaptic events when exposed to …

Steady-state activation and modulation of the concatemeric α1β2γ2L GABAA receptor

AL Germann, SR Pierce, AB Burbridge… - Molecular …, 2019 - ASPET
The two-state coagonist model has been successfully used to analyze and predict peak current
responses of the γ-aminobutyric acid type A (GABA A ) receptor. The goal of the present …

[HTML][HTML] Activation of the Rat α1β2ε GABAA Receptor by Orthosteric and Allosteric Agonists

AL Germann, AB Burbridge, SR Pierce, G Akk - Biomolecules, 2022 - mdpi.com
GABA A receptors are a major contributor to fast inhibitory neurotransmission in the brain. The
receptors are activated upon binding the transmitter GABA or allosteric agonists including …

Analysis of modulation of the ρ1 GABAA receptor by combinations of inhibitory and potentiating neurosteroids reveals shared and distinct binding sites

AL Germann, DE Reichert, AB Burbridge… - Molecular …, 2020 - ASPET
The ρ1 GABA A receptor is prominently expressed in the retina and is present at lower levels
in several brain regions and other tissues. Although the ρ1 receptor is insensitive to many …

Retroperitoneal actinomycosis masquerading as inflammatory pseudotumor

J Radhi, N Hadjis, L Anderson, B Burbridge… - Journal of pediatric …, 1997 - Elsevier
Inflammatory pseudotumors present clinically as mass lesions and microscopically show a
spectrum of nonspecific inflammatory and regenerative changes. When the mesentery or …

The role of the matrix metalloproteinases during in vitro vessel formation

MF Burbridge, F Coge, JP Galizzi, JA Boutin, DC West… - Angiogenesis, 2002 - Springer
… Samples were normalised before PCR with respect to the reversetranscribed b-actin mRNA
levels. For this, the 20-, 25and 30-cycle b-actin amplification products for each sample were …

Only a subset of Met-activated pathways are required to sustain oncogene addiction

A Bertotti, MF Burbridge, S Gastaldi, F Galimi, D Torti… - Science …, 2009 - science.org
Tumor onset and progression require the accumulation of many genetic and epigenetic
lesions. In some cases, however, cancer cells rely on only one of these lesions to maintain their …

The Impact of Breast Cancer Screening on Sleep, Affect, and Immune Functioning

C Burbridge - 2011 - digitalcommons.lib.uconn.edu
Despite great strides that have been made over the past several decades in terms of diagnosis
and treatment, breast cancer remains the most commonly diagnosed cancer in American …

[PDF][PDF] Recent Titles in Contributions in Psychology

…, VA Koltsova, YN Oleinik, CS Reimer, S Ariel - 2002 - academia.edu
This book fills a void. There is no book available that focuses on brief treatments for the
traumatized. There are other works on brief treatment, but the focus is on a general clinical …

Cortical somatostatin interneuron subtypes form cell-type-specific circuits

…, K Kullander, DA Stafford, E Macosko, F Chen, B Rudy… - Neuron, 2023 - cell.com
… Viral labeling of IT/PT neurons and PV interneurons B Slice preparation and brain slice
recording B Optogenetic mapping B Biocytin filling and staining B Retrograde monosynaptic …