Dual action of neutrophil gelatinase–associated lipocalin

…, K Mori, JY Li, A Kalandadze… - Journal of the …, 2007 - journals.lww.com
Neutrophil gelatinase–associated lipocalin (NGAL) is expressed and secreted by immune
cells, hepatocytes, and renal tubular cells in various pathologic states. NGAL exerts …

Neutrophil gelatinase-associated lipocalin-mediated iron traffic in kidney epithelia

KM Schmidt-Ott, K Mori, A Kalandadze… - Current opinion in …, 2006 - journals.lww.com
NGAL is rapidly and massively induced in renal epithelial injury and NGAL: siderophore:
iron complexes may comprise a physiological renoprotective mechanism. The data have …

The Ngal reporter mouse detects the response of the kidney to injury in real time

…, G Gong, Y Liu, R Kulkarni, K Mori, A Kalandadze… - Nature medicine, 2011 - nature.com
Many proteins have been proposed to act as surrogate markers of organ damage, yet for
many candidates the essential biomarker characteristics that link the protein to the injured …

Iron traffics in circulation bound to a siderocalin (Ngal)–catechol complex

…, T Leete, R Kulkarni, X Li, B Lee, A Kalandadze… - Nature chemical …, 2010 - nature.com
The lipocalins are secreted proteins that bind small organic molecules. Scn-Ngal (also known
as neutrophil gelatinase associated lipocalin, siderocalin, lipocalin 2) sequesters bacterial …

Regulation of the glial Na+-dependent glutamate transporters by cyclic AMP analogs and neurons

BD Schlag, JR Vondrasek, M Munir, A Kalandadze… - Molecular …, 1998 - ASPET
Sodium-dependent transport into astrocytes is critical for maintaining the extracellular
concentrations of glutamate below toxic levels in the central nervous system. In this study, the …

[HTML][HTML] Protein kinase C activation decreases cell surface expression of the GLT-1 subtype of glutamate transporter: requirement of a carboxyl-terminal domain and …

A Kalandadze, Y Wu, MB Robinson - Journal of Biological Chemistry, 2002 - ASBMB
Na + -dependent glutamate transporters are required for the clearance of extracellular glutamate
and influence both physiological and pathological effects of this excitatory amino acid. …

[HTML][HTML] Expression of recombinant HLA-DR2 molecules: Replacement of the hydrophobic transmembrane region by a leucine zipper dimerization motif allows the …

A Kalandadze, M Galleno, L Foncerrada… - Journal of Biological …, 1996 - ASBMB
Major histocompatibility complex (MHC) class II molecules are membrane-anchored heterodimers
that present peptides on the surface of antigen presenting cells to T cells. Soluble HLA…

Identification of motifs involved in endoplasmic reticulum retention–forward trafficking of the GLT-1 subtype of glutamate transporter

A Kalandadze, Y Wu, K Fournier… - Journal of …, 2004 - Soc Neuroscience
Glutamate transporters may exist as homomultimers, but little is known about the mechanisms
that ensure proper assembly and surface expression. In the present study, we investigated …

Expression and crystallization of the complex of HLA-DR2 (DRA, DRB1* 1501) and an immunodominant peptide of human myelin basic protein

…, KJ Smith, J Pyrdol, A Kalandadze… - Proceedings of the …, 1998 - National Acad Sciences
HLA-DR2 is associated with susceptibility to multiple sclerosis (MS). A peptide from human
myelin basic protein (MBP, residues 85–99) was previously found to bind to purified HLA-…

Topoisomerase I is associated with the regulatory region of transcriptionally active SV 40 minichromosomes

YS Vassetzky, VV Bakayev, AG Kalandadze… - Molecular and Cellular …, 1990 - Springer
Proteins bound to SV 40 DNA in sarkosyl-treated nuclei have been studied. The major
component is topoisomerase I, a 60–70 kDa protein which possesses a strong DNA-nicking …