Binding of 3H-naloxone in the mouse brain: effect of ions and tolerance development

RJ Hitzemann, BA Hitzemann, HH Loh - Life Sciences, 1974 - Elsevier
The binding of 3 H-naloxone (spec. act. 5.2 Ci/mmol) in a crude mitochondrial fraction of the
whole mouse brain was examined. Binding was reversed by the narcotic agonists …

Phosphatidate as a molecular link between depolarization and neurotransmitter release in the brain

RA Harris, J Schmidt, BA Hitzemann, RJ Hitzemann - Science, 1981 - science.org
Phosphatidate, a neuronal phospholipid, stimulated the uptake of calcium by nerve terminals
isolated from the striatum of rat brain. This effect was not produced by other phospholipids …

On the relationship between D2 receptor density and neuroleptic-induced catalepsy among eight inbred strains of mice.

SJ Kanes, BA Hitzemann, RJ Hitzemann - Journal of Pharmacology and …, 1993 - ASPET
The present study assesses the relationships among ED50 to neuroleptic-induced catalepsy
and regional brain D1 and D2 dopamine receptor binding for eight inbred strains of mice (A…

Determination of chlorpromazine and its major metabolites by gas chromatography/mass spectrometry: application to biological fluids

…, FD Klein, TL Nguyen, BA Hitzemann… - Biomedical mass …, 1985 - Wiley Online Library
A method for the quantitative determination of chlorpromazine and five of its major metabolites
in a single sample of biological fluid in the ng/ml range has been developed utilizing gas …

Effects of withdrawal from chronic amphetamine intoxication on exploratory and stereotyped behaviors in the rat

RJ Hitzemann, LF Tseng, BA Hitzemann… - …, 1977 - Springer
Rats were administered 3, 6, and 12 mg/kg of d-amphetamine sc twice daily on a weekly
increasing staircase schedule. On days 1, 7, 14, and 28 after the last injection of amphetamine …

Influence of prenatal d-amphetamine administration on development and behavior of rats

BA Hitzemann, RJ Hitzemann, DA Brase, HH Loh - Life Sciences, 1976 - Elsevier
Beginning on the fifth day of gestation, rats were administered 1 or 3 mg/kg of d -amphetamine
sulfate sc twice daily until term. The administration of d -amphetamine caused a dose-…

[PDF][PDF] Repeated electroconvulsive shock: effect on sodium dependency and regional distribution of opioid-binding sites.

RJ Hitzemann, BA Hitzemann, S Blatt… - Molecular …, 1987 - Citeseer
The effects of single and repeated electroconvulsive shock (ECS) on the binding of [3H]
diprenorphine to rat brain membranes was studied. Repeated but not single ECS significantly …

ON THE SPECIFICITY OF TRYPSIN (EC 3.4.4.4) OF NERVE ENDING PARTICLES TO INHIBIT NOREPINEPHRINE TRANSPORT1,2

BA Hitzemann, RJ Hitzemann… - Journal of …, 1975 - Wiley Online Library
The Na + and energy dependent uptake of norepinephrine into cortical rat brain homogenates
or purified nerve ending particles (NEP) is reduced by prior trypsin treatment. In contrast, …

Effect of pentobarbital on regional brain phospholipid synthesis

R Natsuki, RJ Hitzemann, BA Hitzemann… - Biochemical …, 1977 - Elsevier
Rats were given 45 mg/kg ip sodium pentobarbital 15 min prior to the intraventricular injection
of 200 μCi [ 32 P]phosphoric acid and 50 μCi [ 3 H]glycerol. The animals were sacrificed 1 …

Activation of orbital and medial prefrontal cortex by methylphenidate in cocaine-addicted subjects but not in controls: relevance to addiction

…, C Wong, YS Ding, R Hitzemann… - Journal of …, 2005 - Soc Neuroscience
… prefrontal cortex [Brodmann's area (BA) 25 and medial BA 11], where … In addicted subjects,
increases in BA 25 were also … of BA 25 (region involved with emotional reactivity) and BA 11 (…