Bis(isopropyloxymethylcarbonyl) 9-R-(2-phosphonomethoxypropyl)adenine [bis(POC)PMPA]
has been identified as a novel prodrug of PMPA. The anti-human immunodeficiency virus …

Fetal growth rates, relative proportions of the gravid uterus, average maternal and neonatal
weights, neonatal growth rates, and estimates of maternal milk production at the peak of …

Bis(pivaloyloxymethyl) [bis(pom)] derivatives of various acyclic nucleoside phosphonates--9-(2-phosphonylmethoxyethyl)adenine
(PMEA), 9-(2-phosphonylmethoxypropyl)adenine (…

9-(2-Phosphonylmethoxyethyl)adenine (PMEA), the acyclic phosphonate analog of adenine
monophosphate, is a promising antiviral drug with activity against herpesviruses, Epstein-…

The present study had two major objectives:(a) to explore the role of language in peer
interaction and play of deaf children and (b) to examine the effect of three partner characteristics (…

The cellular uptake of phosphonylmethoxypropyl cytosine (HPMPC) was characterized to
gain insight into the molecular properties that allow this anticytomegalovirus drug to permeate …

All nucleoside reverse transcriptase inhibitors (NRTI) must first be metabolized to their
triphosphate forms in order to be active against HIV. Zidovudine (ZDV), abacavir (ABC) and …

A novel assay using high pressure liquid chromatography (HPLC) coupled to mass
spectrometer (MS) detection was developed and validated for the rifamycin anti-tuberculosis …

Objective. As tenofovir disoproxil fumarate substantially increases plasma concentrations of
didanosine in patients with human immunodeficiency virus‐1 infection, we sought to …

In this report, we describe a new method to measure intracellular zidovudine triphosphate (ZDV-TP)
levels in peripheral blood mononuclear cells (PBMCs) from patients treated with …