In the female Sprague‐Dawley rat uterus 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD) and
related compounds exhibited a broad spectrum of antioestrogenic responses. For example 2,…

Abstract Treatment of 25-day-old female Sprague-Dawley rats with 2,3,7,8-tetrachlorodibenzo-p-dioxin
(TCDD) significantly lowered constitutive uterine peroxidase activity and …

… In male Long Evans rats at a dose level as high as 500 pmol/kg, MCDF did not cause any
significant changes in organ weights or body weights (B. Astroff, unpublished results) and only …

In addition to being one of the most toxic chemicals known, 2,3,7,8-tetrachlorodibenzo-p-dioxin
(TCDD) is the most potent inducer of rat liver microsomal cytochrome P-4501A1 (P-450c)…

Adriamycin was internalized in canine red blood cells (RBC) by two procedures involving (a)
simple diffusion of the drug into cells and (b) hypotonic dialysis followed by isotonic …

6-Methyl-i, 3, 8-trichlorodibenzofuran(MCDF) binds with moderate affinity to the aryl
hydrocarbon(Ah) receptor protein (4.9 x 10-8 M) but is a weak Ah receptor agonist. Cotreatment of …

Abstract Treatment of immature female Sprague-Dawley rats with 17β-estradiol (5 μg/animal)
resulted in an increase in uterine epidermal growth factor (EGF) receptor binding activity. …

Acute administration of 17β-estradiol (5 μg/rat) to 25-day-old female Sprague-Dawley rats
resulted in an increase of uterine mRNA for the cellular oncogene c-fos. The c-fos mRNA …

6-Methyl-1,3,8-trichlorodibenzofuran (MCDF), 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
and TCDD plus MCDF were administered to C57BL/6 mice and their effects on several aryl …

The activities of several 6-substituted-1,3,8-trichlorodibenzofurans (CDFs) as partial
antagonists of the induction of hepatic microsomal aryl hydrocarbon hydroxylase (AHH) and …