… causes similar defects in B-cell development and activation as those observed in B cells
lacking BTK and TEC (which is partially redundant with BTK in mouse B cells). Consistent with …

… This negatively regulates protein kinase B (AKT), phosphatidylinositol-dependent kinase-1
(PDK1), and other PIP3-dependent moieties to inhibit growth, protein synthesis, cell cycle …

… There are two splice variants of IR, A (IR-A) and B (IR-B), of which the former is believed
to play more of a mitogenic role whereas the latter has been linked to metabolism. IR-A …

… Hopkins is widely recognized as the leading authority on the subject; in this thoroughly
revised Twelfth Edition, he provides all the updates you need to stay current on the latest …

… b Five patients were mistakenly randomized twice (3 to the conventional oxygen therapy
group and 2 to the high-flow nasal oxygen group), but did not receive treatment. These patients …

Electro-osmosis has been used to pump solvents in both thin-layer and high-speed liquid
chromatography. The advantages of this technique over conventional methods of driving …

Optical-based distance measurements are essential for tracking biomolecular conformational
changes, drug discovery, and cell biology. Traditional Förster resonance energy transfer (…

Precision medicine is an approach that takes into account the influence of individuals' genes,
environment, and lifestyle exposures to tailor interventions. Here, we describe the …

Protein phosphorylation is one of the most widespread post-translational modifications in
biology 1 , 2 . With advances in mass-spectrometry-based phosphoproteomics, 90,000 sites of …

This textbook is designed for a one-or two-semester course in applied statistics. The theory
and methods are applicable to empirical research in many disciplines. We have drawn …