User profiles for Bernhard Bettler

Bernhard Bettler

Verified email at unibas.ch
Cited by 28108

GABAB-receptor subtypes assemble into functional heteromeric complexes

…, S Bischoff, A Kulik, R Shigemoto, A Karschin, B Bettler - Nature, 1998 - nature.com
B-type receptors for the neurotransmitter GABA (γ-aminobutyric acid) inhibit neuronal activity
through G-protein-coupled second-messenger systems, which regulate the release of …

Expression cloning of GABAB receptors uncovers similarity to metabotropic glutamate receptors

…, G McMaster, C Angst, H Bittiger, W Froestl, B Bettler - Nature, 1997 - nature.com
GABA (γ-amino-butyric acid), the principal inhibitory neurotransmitter in the brain, signals
through ionotropic (GABA A /GABA C ) and metabotropic (GABA B ) receptor systems. Here we …

The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors

…, JM Beaulieu, KE Bernstein, B Bettler… - British journal of …, 2021 - Wiley Online Library
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial
publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key …

Molecular Structure and Physiological Functions of GABAB Receptors

B Bettler, K Kaupmann, J Mosbacher… - Physiological …, 2004 - journals.physiology.org
GABA B receptors are broadly expressed in the nervous system and have been implicated
in a wide variety of neurological and psychiatric disorders. The cloning of the first GABA B …

The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors

…, JM Beaulieu, KE Bernstein, B Bettler… - British journal of …, 2019 - Wiley Online Library
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial
publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 …

[HTML][HTML] Epilepsy, hyperalgesia, impaired memory, and loss of pre-and postsynaptic GABAB responses in mice lacking GABAB (1)

…, S Bischoff, K Kaupmann, H van der Putten, B Bettler - Neuron, 2001 - cell.com
GABA B (γ-aminobutyric acid type B) receptors are important for keeping neuronal excitability
under control. Cloned GABA B receptors do not show the expected pharmacological …

GABAB receptors–the first 7TM heterodimers

…, KA Jones, K Kaupmann, B Bettler - Trends in pharmacological …, 1999 - cell.com
Fiona H. Marshall, Kenneth A. Jones, Klemens Kaupmann and Bernhard Bettler relative to
GABABR1. It is possible that GABABR1 can function as a monomer in some discrete regions …

Cloning of a novel glutamate receptor subunit, GluR5: expression in the nervous system during development

B Bettler, J Boulter, I Hermans-Borgmeyer… - Neuron, 1990 - cell.com
We have isolated cDNAs encoding a glutamate receptor subunit, designated CIuR5, displaying
40%-41% amino acid identity with the kainate/AMPA receptor subunits CIuRl, GIuR2, …

Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice

…, I Bureau, C Maron, FH Gage, JR Mann, B Bettler… - Nature, 1998 - nature.com
l-glutamate, the neurotransmitter of the majority of excitatory synapses in the brain, acts on
three classes of ionotropic receptors: NMDA (N-methyl-d-aspartate), AMPA (α-amino-3-…

Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins

Y Stern-Bach, B Bettler, M Hartley, PO Sheppard… - Neuron, 1994 - cell.com
By exchanging portions of the AMPA receptor subunit GluR3 and the kainate receptor subunit
GluR6, we have identified two discontinuous segments of approximately 150 amino acid …