Tiotidine, a Histamine H2 Receptor Inverse Agonist That Binds with High Affinity to an Inactive G-Protein—Coupled Form of the Receptor. Experimental Support for the …
F Monczor, N Fernandez, BL Legnazzi, ME Riveiro… - Molecular …, 2003 - ASPET
Knowing the importance for research and pharmacological uses of proper ligand classification
into agonists, inverse agonists, and antagonists, the aim of this work was to study the …
into agonists, inverse agonists, and antagonists, the aim of this work was to study the …
Histamine H2 receptor desensitization: involvement of a select array of G protein-coupled receptor kinases
C Shayo, N Fernandez, BL Legnazzi, F Monczor… - Molecular …, 2001 - ASPET
The histamine H2 receptor (H2r) belongs to the heptahelical receptor family; upon agonist
binding, members of this family activate a G protein and the downstream effector adenylyl …
binding, members of this family activate a G protein and the downstream effector adenylyl …
Histamine Modulates the Expression of c-fosthrough Cyclic AMP Production via the H2 Receptor in the Human Promonocytic Cell Line U937
…, C Davio, A Brodsky, AG Mladovan, BL Legnazzi… - Molecular …, 1997 - ASPET
We examined the effects of histamine and its agonists on the expression of the c-fos and c-myc
proto-oncogenes at the transcriptional and translational levels in the human …
proto-oncogenes at the transcriptional and translational levels in the human …
The time-course of cyclic AMP signaling is critical for leukemia U-937 cell differentiation
C Shayo, BL Legnazzi, F Monczor, N Fernández… - Biochemical and …, 2004 - Elsevier
The regulation of the cAMP signaling is intimately involved in several cellular processes,
including cell differentiation. Here, we provide strong evidence supporting that the time-course …
including cell differentiation. Here, we provide strong evidence supporting that the time-course …
Forskolin induces U937 cell line differentiation as a result of a sustained cAMP elevation
A Brodsky, C Davio, C Shayo, BL Legnazzi… - European journal of …, 1998 - Elsevier
The present study examines the effects of forskolin on U937 cell differentiation. We recently
reported that dibutyryl cAMP (dbcAMP), but not cAMP-elevating agents such as histamine, …
reported that dibutyryl cAMP (dbcAMP), but not cAMP-elevating agents such as histamine, …
Rapid desensitization and slow recovery of the cyclic AMP response mediated by histamine H2 receptors in the U937 cell line
BL Legnazzi, C Shayo, F Monczor, ME Martin… - Biochemical …, 2000 - Elsevier
The present study focused on the desensitization process of the H 2 receptor in U937 cells
and the recovery of the cyclic AMP (cAMP) response. Treatment of U937 leukemic cells with …
and the recovery of the cyclic AMP (cAMP) response. Treatment of U937 leukemic cells with …
Reduction of G protein-coupled receptor kinase 2 expression in U-937 cells attenuates H2 histamine receptor desensitization and induces cell maturation
N Fernández, F Monczor, B Lemos, C Notcovich… - Molecular …, 2002 - ASPET
Histamine and H2 agonists transiently induce an important cAMP response in promonocytic
U-937 cells but fail to induce monocytic differentiation because of a rapid receptor …
U-937 cells but fail to induce monocytic differentiation because of a rapid receptor …
H1 and H2 histamine receptors mediate the production of inositol phosphates but not cAMP in human breast epithelial cells
C Davio, A Mladovan, B Lemos, F Monczor… - Inflammation …, 2002 - Springer
Objective: In the present work we studied the H 1 and H 2 histamine receptor expression
and function in HBL-100 and MCF-10A cells, derived from non-tumorigenic human breast …
and function in HBL-100 and MCF-10A cells, derived from non-tumorigenic human breast …
[HTML][HTML] Pertussistoxin-sensitive Signalwege von alpha-MSH und AgRP an Melanocortin-4-Rezeptoren
DJ Heling - 2012 - nbn-resolving.org
… Federico Monczor, Natalia Fernandez, Bibiana Lemos Legnazzi, Maria Eugenia Riveiro,
Alberto Baldi, Carina Shayo, and Carlos Davio. Tiotidine, a histamine h2 receptor inverse …
Alberto Baldi, Carina Shayo, and Carlos Davio. Tiotidine, a histamine h2 receptor inverse …
[CITATION][C] Jeras, Matjaz, 717 Jiménez-Vega, Florinda, 681 Jung, Christiane, 810
A Abbasi, HN Achuth, N Acosta-Rivero, H Akazawa…