Urotensin-II (U-II), the most potent mammalian vasoconstrictor identified, and its receptor, UT,
exhibits increased expression in cardiac tissue and plasma in congestive heart failure (CHF…

The nucleotide selectivities of the human P2Y 4 (hP2Y 4 ) and rat P2Y 4 (rP2Y 4 ) receptor
stably expressed in 1321N1 human astrocytoma cells were determined by measuring …

UTP is a potent full agonist at both the human P2Y 4 (hP2Y 4 ) and rat P2Y 4 (rP2Y 4 )
receptor. In contrast, ATP is a potent full agonist at the rP2Y 4 receptor but is a similarly potent …

The functional activity of the peptidic neuromedin B receptor antagonist BIM‐23127 was
investigated at recombinant and native urotensin‐II receptors (UT receptors). Human urotensin‐…

In an effort to identify endogenous, native mammalian urotensin‐II (U‐II) receptors (UT), a
diverse range of human, primate and rodent cell lines (49 in total) were screened for the …

Of the two major isoforms of the angiotensin II receptors, type 1 (AT 1 ) and type 2 (AT 2 ), little
is known about the structure and features of AT 2 . We cloned a mouse AT 2 cDNA from a …

Human urotensin‐II (hU‐II), a cyclic undecapeptide, is amongst the most potent mammalian
vasoconstrictors identified, suggesting that hU‐II and its G‐protein‐coupled receptor (UT) …

A recently cloned G protein-coupled receptor (named the p2y7 receptor) with relatively low
sequence identity to previously cloned P2Y receptors was proposed to be a member of this …

SB-710411 (Cpa-c[d-Cys-Pal-d-Trp-Lys-Val-Cys]-Cpa-amide) inhibited [ 125 I]urotensin-II rat
and monkey UT receptor binding (pK i s 7.50±0.07 and 6.82±0.06). However, whereas SB-…

Fossil markings of doubtful origin were found in strand deposits of the Carmelo series (Upper
Cretaceous [?]) at Point Lobos, California. The purpose of this article is to show that some …