Synaptic vesicle endocytosis (SVE) is triggered by calcineurin-mediated dephosphorylation
of the dephosphin proteins. SVE is maintained by the subsequent rephosphorylation of the …

Dynamin is a GTPase enzyme involved in membrane constriction and fission during
endocytosis. Phospholipid binding via its pleckstrin homology domain maximally stimulates …

The septins are GTPase enzymes with multiple roles in cytokinesis, cell polarity or exocytosis.
The proteins from the mammalian septin genes are called Sept1–10. Most are expressed …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder in which patients lose
motor functions due to progressive loss of motor neurons in the cortex, brainstem, and spinal …

The large‐scale resolution and detection of proteins from complex native mixtures is fundamental
to quantitative proteomic analyses. Comprehensive analyses depend on careful tissue …

Small molecules modulating synaptic vesicle endocytosis (SVE) may ultimately be useful for
diseases where pathological neurotransmission is implicated. Only a small number of …

Dynamin I is phosphorylated in nerve terminals exclusively in the cytosolic compartment
and in vitro by protein kinase C (PKC). Dephosphorylation is required for synaptic vesicle …

Calcineurin is a phosphatase that is activated at the last known stage of mitosis, abscission.
Among its many substrates, it dephosphorylates dynamin II during cytokinesis at the …

Maintaining synaptic transmission requires replenishment of docked synaptic vesicles
within the readily releasable pool (RRP) from synaptic vesicle clusters in the synapsin-bound …

A significant gap in the knowledge of zinc homeostasis exists for breast cancer cells. In this
study, we investigated the transcriptomic response of the luminal breast cancer cells (MCF-7) …