Analyzing the type and frequency of patient‐specific mutations that give rise to Duchenne
muscular dystrophy (DMD) is an invaluable tool for diagnostics, basic scientific research, trial …

… Charles Bladen is an international academic, researcher and business consultant … discussion
about events management professionalism (Bladen and Kennel 2014; Bladen, et al. 2012). …

Objective The relationship between genetic variation in the T‐type calcium channel gene
CACNA1H and childhood absence epilepsy is well established. The purpose of this study was …

T-type calcium channels are essential contributors to the transmission of nociceptive signals
in the primary afferent pain pathway. Here, we show that T-type calcium channels are …

Background: Recent short-term clinical trials in patients with Duchenne Muscular Dystrophy
(DMD) have indicated greater disease variability in terms of progression than expected. In …

We examined ion channels derived from a chloroform extract of isolated, dehydrated rat
liver mitochondria. The extraction method was previously used to isolate a channel-forming …

… (C) Ensemble steady state inactivation curves obtained with wild-type and mutant Ca v 3.2
channels. The currents were elicited by inactivating the channel population (−10mV for 1.5 …

… The reactions were assembled without DNA and preincubated for 5 min at 37 C, DNA was
added, and incubation was continued for 30 min at 37 C. The products were analyzed as …

Spinal muscular atrophy (SMA) is an autosomal recessive genetic disorder characterised by
the degeneration of motor neurons and progressive muscle weakness. It is caused by …

… (DMEM) containing 25 mM D-glucose, 10 % fetal bovine serum, and 1 % penicillin/streptomycin
(all products were from Invitrogen) and maintained under standard conditions at 37 C in …