The highest level of confidence can be placed in calculatedlog P values when (1) the log P
of a parent solute is known,(2) constants for the required substituent (s) are available, and (3) …

… the most generally obtainable parameter for relative biological activity is log 1/C, where C
is the molar concentration of an organic compound producing a standard biological response …

… In attempting to simplify the presentation of test results in the appendix, we have listed a
single figure which is either log 1/C or log 1/Kicxpp. … Replacing N by C in the 3-deazo …

… C in log 1 ¡C in Table I represents the molar concentration which produces50% reversible
inhibition of dihydrofolate reductase obtained from either L1210/DF8 mouse leukemia or …

… Corwin Hansch,* Antonio Vittoria,1 Carlo Silipo,s and Priscilla Y. C. Jow … We have
assumed that the C=C function is electronegative enough to conferpolar character on …

… In this equation, MR-1, MR-2, and MR-3 refer to the molar refractivities of -NHCORi (or -NHS02Ri),
R2, and OR3 falling in p space as shown in structures in 2a-c. is an indicator variable …

… The substitution at the 2’-position of the C phenyl ring was modelled with an indicator
variable (12,); in fact, the few structural modifications at this position did not allow the use of …

… The QSAR for 83 inhibitors is described by log 1 ¡C = … the variance in log 1/C of the 83
complex modifications of I; hence, 18% of the information in log 1/C cannot be accounted for. This …

A series of 1- and 2-[3-[4-(X)-1-piperazinyl]-propyl]benzotriazoles were prepared and
evaluated for their trazodone-like pharmacological profile; as preliminary pharmacological …

… Thedependent variables (log 1/C) in the equations reported in this paper are all in terms of
the molar concentration causing50% inhibition of enzyme activity. The constants for v and MR …