Nitric oxide activates an Nrf2/sulfiredoxin antioxidant pathway in macrophages

…, AG Planson, C Bouton, J Bignon, C Seguin… - Free Radical Biology …, 2011 - Elsevier
Peroxiredoxins (Prx's) are a family of peroxidases that maintain thiol homeostasis by catalyzing
the reduction of organic hydroperoxides, H 2 O 2 , and peroxynitrite. Under conditions of …

β-Cyclodextrin-functionalized chitosan/alginate compact polyelectrolyte complexes (CoPECs) as functional biomaterials with anti-inflammatory properties

A Hardy, C Seguin, A Brion, P Lavalle… - … applied materials & …, 2018 - ACS Publications
Nowadays, the need for therapeutic biomaterials displaying anti-inflammatory properties to
fight against inflammation-related diseases is continuously increasing. Compact …

Polyarginine as a simultaneous antimicrobial, immunomodulatory, and miRNA delivery agent within polyanionic hydrogel

V Gribova, L Petit, L Kocgozlu, C Seguin… - Macromolecular …, 2022 - Wiley Online Library
Implantation of biomedical devices is followed by immune response to the implant, as well as
occasionally bacterial, yeast, and/or fungal infections. In this context, new implant materials …

[HTML][HTML] RNA aptamers targeting integrin α5β1 as probes for cyto-and histofluorescence in glioblastoma

…, S Martin, I Lelong-Rebel, AM Ray, C Seguin… - … Therapy-Nucleic Acids, 2019 - cell.com
Nucleic acid aptamers are often referred to as chemical antibodies. Because they possess
several advantages, like their smaller size, temperature stability, ease of chemical modification…

11β-Hydroxyprogesterone acts as a mineralocorticoid agonist in stimulating Na+ absorption in mammalian principal cortical collecting duct cells

ME Rafestin-Oblin, J Fagart, A Souque, C Seguin… - Molecular …, 2002 - ASPET
The binding of mineralocorticoid hormones to the mineralocorticoid receptor is the first step
in a cascade of events leading to the stimulation of Na + reabsorption by renal cortical …

A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis

…, F Goncalves, C Carayon, C Seguin… - ACS infectious …, 2021 - ACS Publications
A novel coumarin-based molecule, designed as a fluorescent surrogate of a thiacetazone-derived
antitubercular agent, was quickly and easily synthesized from readily available …

The− 33T→ C polymorphism in intron 7 of the TFPI gene influences the risk of venous thromboembolism, independently of the factor V Leiden and prothrombin …

N Ameziane, C Seguin, D Borgel… - Thrombosis and …, 2002 - thieme-connect.com
We have previously identified, in intron 7 of the TFPI gene, a T to C single-base polymorphism
(−33T→C) which is strongly associated with total circulating TFPI antigen levels. Here we …

Silver Nanoparticle‐Decorated Reduced Graphene Oxide Nanomaterials Exert Membrane Stress and Induce Immune Response to Inhibit the Early Phase of HIV‐1 …

…, A Ridoskova, J Pekarkova, C Seguin… - Advanced Materials …, 2023 - Wiley Online Library
Graphene‐based 2D nanomaterials exhibit unique physicochemical, electric, and optical
properties that facilitate applications in a wide range of fields including material science, …

Optimization of peptide-based cancer vaccine compositions, by sequential screening, using versatile liposomal platform

C Jacoberger-Foissac, H Saliba, C Seguin… - International Journal of …, 2019 - Elsevier
Therapeutic cancer vaccines need thoughtful design to efficiently deliver appropriate
antigens and adjuvants to the immune system. In the current study, we took advantage of the …

Synthesis and Characterization of N‐Heterocyclic Carbene Dithiocarbamate Platinum Complexes with Antitumoral Activity

R Verron, T Achard, C Seguin, S Fournel… - European Journal of …, 2020 - Wiley Online Library
A series of platinum(II) complexes bearing N‐heterocyclic carbene NHC of the type [(NHC)PtX(L)]
where L is a dithiocarbamate ligand and X iodide were prepared and fully …