Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma

SH Chiou, CC Yu, CY Huang, SC Lin, CJ Liu… - Clinical cancer …, 2008 - AACR
Purpose: Oral squamous cell carcinoma (OSCC), like many solid tumors, contains a
heterogeneous population of cancer cells. Recent data suggest that a rare subpopulation of cancer …

[HTML][HTML] Bmi-1 regulates snail expression and promotes metastasis ability in head and neck squamous cancer-derived ALDH1 positive cells

CC Yu, WL Lo, YW Chen, PI Huang, HS Hsu… - Journal of …, 2011 - hindawi.com
Recent studies suggest that ALDH1 is a putative marker for HNSCC-derived cancer stem
cells. However, the regulation mechanisms that maintain the stemness and metastatic …

Impairment of tumor‐initiating stem‐like property and reversal of epithelial–mesenchymal transdifferentiation in head and neck cancer by resveratrol treatment

…, CH Yu, PN Chen, MY Chou, CC Yu - Molecular nutrition & …, 2012 - Wiley Online Library
Scope Recent reports have demonstrated that head and neck cancer‐derived tumor‐initiating
cells (HNC‐TICs) presented high tumorigenic, chemoradioresistant, metastatic properties, …

[HTML][HTML] Arecoline enhances miR-21 to promote buccal mucosal fibroblasts activation

…, CC Yu, PL Hsieh, YW Liao, PM Chu, CH Yu… - Journal of the Formosan …, 2021 - Elsevier
Background/purpose Oral submucous fibrosis (OSF) is an irreversible fibrosis disease and
a potentially malignant disorder in the oral cavity. Various studies have shown that miR-21 …

Cancer-derived exosomes: their role in cancer biology and biomarker development

VC Kok, CC Yu - International Journal of Nanomedicine, 2020 - Taylor & Francis
Exosomes are a subset of tiny extracellular vesicles manufactured by all cells and are
present in all body fluids. They are produced actively in tumor cells, which are released and …

Markedly increased Oct4 and Nanog expression correlates with cisplatin resistance in oral squamous cell carcinoma

LL Tsai, CC Yu, YC Chang, CH Yu… - Journal of Oral …, 2011 - Wiley Online Library
J Oral Pathol Med (2011) 40: 621–628 Background: Oral squamous cell carcinoma (OSCC)
is the sixth most prevalent cancer worldwide. Cancer stem cells (CSC) model theoretically …

Let-7d functions as novel regulator of epithelial-mesenchymal transition and chemoresistant property in oral cancer

…, LL Tsai, YC Chang, SW Lu, CH Yu… - Oncology …, 2011 - spandidos-publications.com
Oral squamous cell carcinoma (OSCC) is a prevalent cancer worldwide. Let-7 family has been
shown to function as a tumor suppressor through regulating multiple oncogenic signaling. …

[HTML][HTML] Tumorsphere as an effective in vitro platform for screening anti-cancer stem cell drugs

CH Lee, CC Yu, BY Wang, WW Chang - Oncotarget, 2016 - ncbi.nlm.nih.gov
Cancer stem cells (CSCs) are a sub-population of cells within cancer tissues with tumor
initiation, drug resistance and metastasis properties. CSCs also have been considered as the …

MicroRNA‐200c attenuates tumour growth and metastasis of presumptive head and neck squamous cell carcinoma stem cells

WL Lo, CC Yu, GY Chiou, YW Chen… - The Journal of …, 2011 - Wiley Online Library
MicroRNA‐200c (miR200c) is emerging as an important regulator of tumourigenicity and
cancer metastasis with a strong capacity for inducing epithelial–mesenchymal transitions. …

Cationic polyurethanes-short branch PEI-mediated delivery of Mir145 inhibited epithelial–mesenchymal transdifferentiation and cancer stem-like properties and in …

…, CI Wong, LM Tseng, PI Huang, CC Yu… - Journal of controlled …, 2012 - Elsevier
The high invasiveness and frequent recurrence of lung adenocarcinoma (LAC) are major
reasons for treatment failures and poor prognoses. Alterations in microRNAs (miRNAs) …