Mitochondrial CB1 receptors regulate neuronal energy metabolism

…, A Cannich, E Hebert-Chatelain, C Mulle… - Nature …, 2012 - nature.com
The mammalian brain is one of the organs with the highest energy demands, and mitochondria
are key determinants of its functions. Here we show that the type-1 cannabinoid receptor (…

[HTML][HTML] Early synaptic deficits in the APP/PS1 mouse model of Alzheimer's disease involve neuronal adenosine A2A receptors

…, A Frick, UV Nägerl, RA Cunha, C Mulle - Nature …, 2016 - nature.com
Synaptic plasticity in the autoassociative network of recurrent connections among hippocampal
CA3 pyramidal cells is thought to enable the storage of episodic memory. Impaired …

Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice

C Mulle, A Sailer, I Pérez-Otaño, H Dickinson-Anson… - Nature, 1998 - nature.com
l-glutamate, the neurotransmitter of the majority of excitatory synapses in the brain, acts on
three classes of ionotropic receptors: NMDA (N-methyl-d-aspartate), AMPA (α-amino-3-…

[HTML][HTML] Adenosine A2A receptors are essential for long-term potentiation of NMDA-EPSCs at hippocampal mossy fiber synapses

N Rebola, R Lujan, RA Cunha, C Mulle - Neuron, 2008 - cell.com
The physiological conditions under which adenosine A 2A receptors modulate synaptic
transmission are presently unclear. We show that A 2A receptors are localized postsynaptically …

Activity‐dependent synaptic plasticity of NMDA receptors

N Rebola, BN Srikumar, C Mulle - The Journal of physiology, 2010 - Wiley Online Library
… inline image Christophe Mulle is a cellular neurobiologist with expertise in cellular
electrophysiology of synaptic transmission and plasticity, receptor cell biology and the generation of …

Operation and plasticity of hippocampal CA3 circuits: implications for memory encoding

N Rebola, M Carta, C Mulle - Nature Reviews Neuroscience, 2017 - nature.com
The CA3 region of the hippocampus is important for rapid encoding of memory. Computational
theories have proposed specific roles in hippocampal function and memory for the sparse …

Presynaptic glutamate receptors: physiological functions and mechanisms of action

PS Pinheiro, C Mulle - Nature Reviews Neuroscience, 2008 - nature.com
Glutamate acts on postsynaptic glutamate receptors to mediate excitatory communication
between neurons. The discovery that additional presynaptic glutamate receptors can modulate …

Kainate receptors coming of age: milestones of two decades of research

A Contractor, C Mulle, GT Swanson - Trends in neurosciences, 2011 - cell.com
Two decades have passed since the first report of the cloning of a kainate-type glutamate
receptor (KAR) subunit. The intervening years have seen a rapid growth in our understanding …

Kainate receptors

P Pinheiro, C Mulle - Cell and tissue research, 2006 - Springer
Kainate receptors form a family of ionotropic glutamate receptors that appear to play a special
role in the regulation of the activity of synaptic networks. This review first describes briefly …

Evidence for" preterminal" nicotinic receptors on GABAergic axons in the rat interpeduncular nucleus

C Lena, JP Changeux, C Mulle - Journal of Neuroscience, 1993 - Soc Neuroscience
Presynaptic nicotinic ACh receptors (nAChRs) are abundant in the nervous system, where
they are thought to regulate the release of various neurotransmitters. Whole-cell recordings …