Cellular mechanisms of nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor regulation and heterologous regulation by N/OFQ

CL Donica, HO Awwad, DR Thakker… - Molecular pharmacology, 2013 - ASPET
The nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor is the fourth and most recently
discovered member of the opioid receptor superfamily that also includes μ, δ, and κ opioid …

EGFR signaling causes morphine tolerance and mechanical sensitization in rats

S Puig, CL Donica, HB Gutstein - ENeuro, 2020 - eneuro.org
The safety and efficacy of opioids are compromised as analgesic tolerance develops.
Opioids are also ineffective against neuropathic pain. Recent reports have suggested that …

[HTML][HTML] Platelet-derived growth factor receptor-β antagonism restores morphine analgesic potency against neuropathic pain

CL Donica, Y Cui, S Shi, HB Gutstein - PLoS One, 2014 - journals.plos.org
Background Chronic, intractable pain is a problem of pandemic proportions. Pain caused by
nerve injuries (neuropathic pain) is extremely difficult to treat. For centuries, opiates such as …

Orphanin FQ/nociceptin activates nuclear factor kappa B

CL Donica, VI Ramirez, HO Awwad, NT Zaveri… - Journal of Neuroimmune …, 2011 - Springer
Endogenous neuropeptide orphanin FQ/nociceptin (OFQ/N) and its receptor, nociceptin
orphanin FQ peptide receptor (NOPr), play a modulatory role throughout the body including …

Sex differences in the Nociceptin/Orphanin FQ system in rat spinal cord following chronic morphine treatment

Y Zhang, CL Donica, KM Standifer - Neuropharmacology, 2012 - Elsevier
Nociceptin/Orphanin FQ (N/OFQ) appears to contribute to the development of morphine
tolerance, as blockade of its actions will block or reverse the process. To better understand the …

Orphanin FQ/Nociceptin Activates Nuclear Factor Kappa B In Neuronal Cells

CL Donica, HO Awwad, H Wu… - The FASEB …, 2010 - Wiley Online Library
Endogenous neuropeptide orphanin FQ/nociceptin (OFQ/N) and its receptor, opioid receptor
like‐1 (ORL1; or Nociceptin orphanin peptide receptor, NOP), have been shown to play a …

[PDF][PDF] Blockade of Nociceptin Signaling Reduces Biochemical, Structural and Cognitive Deficits after Traumatic Brain Injury

…, HO Awwad, VI Ramirez, C Donica, L Gonzalez… - 2010 - researchgate.net
Courtney AC, Courtney MW. A thoracic mechanism of mild traumatic brain injury due to …
Courtney MW, Courtney AC. Working toward exposure thresholds for blast-induced traumatic …

[PDF][PDF] One Hundred Third Annual Spring Commencement University of Wisconsin-La Crosse Sunday, the nineteenth of May, two thousand thirteen

PNT Wirkus - uwlax.edu
The academic apparel worn by faculty and staff in the processional has its origins in the
universities of the Middle Ages. Because the universities grew out of church schools, both faculty …

In vivo detection of inducible nitric oxide synthase in rodent gliomas

RA Towner, N Smith, S Doblas, P Garteiser… - Free Radical Biology …, 2010 - Elsevier
… We thank Courtney L. Quine and Courtney Donica for their assistance in obtaining some of
the animal data during their postgraduate laboratory rotations. We thank Megan Lerner and …

Curriculum-based handwriting programs: A systematic review with effect sizes

C Engel, K Lillie, S Zurawski… - The American Journal of …, 2018 - research.aota.org
Challenges with handwriting can have a negative impact on academic performance, and
these challenges are commonly addressed by occupational therapy practitioners in school …