User profiles for D. E. Reichert

David E. Reichert

3D Imaging
Verified email at 3dimagingllc.com
Cited by 3901

Metal complexes as diagnostic tools

DE Reichert, JS Lewis, CJ Anderson - Coordination Chemistry Reviews, 1999 - Elsevier
This review summarizes some of the developments of metal complexes and metal-complex-bioconjugates
for the diagnosis of disease states that have occurred over the past 10 years. …

Staging the initiation of autoantibody-induced arthritis: a critical role for immune complexes

…, Z Wang, W Nagengast, DE Reichert… - The Journal of …, 2004 - journals.aai.org
In the K/B× N mouse model of arthritis, autoantibodies against glucose-6-phosphate
isomerase cause joint-specific inflammation and destruction. We have shown using micro-positron …

Preparation of 66Ga-and 68Ga-labeled Ga (III)-deferoxamine-folate as potential folate-receptor-targeted PET radiopharmaceuticals

CJ Mathias, MR Lewis, DE Reichert, R Laforest… - Nuclear medicine and …, 2003 - Elsevier
A folate-receptor-targeting radiopharmaceutical, Ga(III)-deferoxamine-folate (Ga-DF-Folate),
was radiolabeled with two positron-emitting isotopes of gallium, cyclotron-produced 66 Ga (…

N-Benzylisatin Sulfonamide Analogues as Potent Caspase-3 Inhibitors:  Synthesis, in Vitro Activity, and Molecular Modeling Studies

…, J Rothfuss, Z Tu, Y Chu, DE Reichert… - Journal of medicinal …, 2005 - ACS Publications
A number of isatin sulfonamide analogues were prepared and their potencies for inhibiting
caspase-1, -3, -6, -7, and -8 were evaluated in vitro. Several compounds displaying a …

Indium(III) and Gallium(III) Complexes of Bis(aminoethanethiol) Ligands with Different Denticities:  Stabilities, Molecular Modeling, and in Vivo Behavior

…, CJ Anderson, TS Pajeau, DE Reichert… - Journal of medicinal …, 1996 - ACS Publications
Complexes of Ga(III) and In(III) radionuclides are widely used in diagnostic imaging. In this
study, the following ligands of denticities 4, 5, and 6 respectively were prepared: N,N‘-bis(2,2-…

[HTML][HTML] Multiple functional neurosteroid binding sites on GABAA receptors

…, MX Qian, B Manion, WWL Cheng, DE Reichert… - PLoS …, 2019 - journals.plos.org
Neurosteroids are endogenous modulators of neuronal excitability and nervous system
development and are being developed as anesthetic agents and treatments for psychiatric …

Mutations of the GABA-A receptor α1 subunit M1 domain reveal unexpected complexity for modulation by neuroactive steroids

G Akk, P Li, J Bracamontes, DE Reichert… - Molecular …, 2008 - ASPET
Neuroactive steroids are among the most efficacious modulators of the mammalian GABA-A
receptor. Previous work has proposed that receptor potentiation is mediated by steroid …

Neurosteroid analog photolabeling of a site in the third transmembrane domain of the β3 subunit of the GABAA receptor

ZW Chen, B Manion, RR Townsend, DE Reichert… - Molecular …, 2012 - ASPET
… After electrophoresis, the gels were cut in vertical columns and sliced in 1-mm horizontal
slices by using a DE 113 manual gel slicer (Hoeffer, San Francisco, CA). Slices were digested …

Subtype selectivity of dopamine receptor ligands: insights from structure and ligand-based methods

…, RH Mach, RR Luedtke, DE Reichert - Journal of chemical …, 2010 - ACS Publications
Subtype selective dopamine receptor ligands have long been sought after as therapeutic
and/or imaging agents for the treatment and monitoring of neurologic disorders. We report …

Assessment of copper nanoclusters for accurate in vivo tumor imaging and potential for translation

…, S Levingston, T Primeau, DE Reichert… - … applied materials & …, 2019 - ACS Publications
… Furthermore, de-identified human TNBC tissues were used to assess the CXCR4 binding
capability of 64 Cu-CuNCs-FC131 and highlight the potential for future translation. …