User profiles for D. G. Deutsch

Dale Deutsch

stony brook university
Verified email at stonybrook.edu
Cited by 10941

The fatty acid amide hydrolase (FAAH)

DG Deutsch, N Ueda, S Yamamoto - Prostaglandins, Leukotrienes and …, 2002 - Elsevier
The fatty acid amide hydrolase (FAAH), is the enzyme responsible for the hydrolysis of
anandamide, an endocannabinoid. The FAAH knockout, the assays for FAAH, the activity of its …

The fatty acid amide hydrolase (FAAH)

…, RA Puffenbarger, S Yamamoto, DG Deutsch - Chemistry and physics of …, 2000 - Elsevier
The topic of this review is fatty acid amide hydrolase (FAAH), one of the best-characterized
enzymes involved in the hydrolysis of bioactive lipids such as anandamide, 2-…

Endocannabinoid tone versus constitutive activity of cannabinoid receptors

…, RE Hampson, NM Ulloa, DG Deutsch - British journal of …, 2011 - Wiley Online Library
This review evaluates the cellular mechanisms of constitutive activity of the cannabinoid (CB)
receptors, its reversal by inverse agonists, and discusses the pitfalls and problems in the …

Plasminogen: purification from human plasma by affinity chromatography

DG Deutsch, ET Mertz - Science, 1970 - science.org
Plasminogen was prepared from human plasma by affinity chromatography on L-lysine-substituted
Sepharose. Thirty milligrams of plasminogen, with a specific activity of 100 …

Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist

DG Deutsch, SA Chin - Biochemical pharmacology, 1993 - Elsevier
Enzymatic activities have been identified which catalyze both the hydrolysis and synthesis of
arachidonylethanolamide (anandamide). Anandamide was taken up by neuroblastoma and …

Production and physiological actions of anandamide in the vasculature of the rat kidney.

DG Deutsch, MS Goligorsky, PC Schmid… - The Journal of …, 1997 - Am Soc Clin Investig
The endogenous cannabinoid receptor agonist anandamide is present in central and
peripheral tissues. As the kidney contains both the amidase that degrades anandamide and …

Identification of intracellular carriers for the endocannabinoid anandamide

…, ST Glaser, DG Deutsch - Proceedings of the …, 2009 - National Acad Sciences
The endocannabinoid anandamide (arachidonoyl ethanolamide, AEA) is an uncharged
neuromodulatory lipid that, similar to many neurotransmitters, is inactivated through its cellular …

[HTML][HTML] Fatty acid-binding proteins (FABPs) are intracellular carriers for Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD)

…, JT Miyauchi, SE Tsirka, I Ojima, DG Deutsch - Journal of Biological …, 2015 - ASBMB
Δ 9 -Tetrahydrocannabinol (THC) and cannabidiol (CBD) occur naturally in marijuana (Cannabis)
and may be formulated, individually or in combination in pharmaceuticals such as …

Evidence against the presence of an anandamide transporter

…, KM Studholme, DG Deutsch - Proceedings of the …, 2003 - National Acad Sciences
On the basis of temperature dependency, saturability, selective inhibition, and substrate
specificity, it has been proposed that an anandamide transporter exists. However, all of these …

Fatty acid amide hydrolase is located preferentially in large neurons in the rat central nervous system as revealed by immunohistochemistry

…, MC Saņudo-Peņa, CJ Hillard, DG Deutsch… - Neuroscience …, 1998 - Elsevier
The distribution in the rat brain of fatty acid amide hydrolase (FAAH) an enzyme that
catalyzes the hydrolysis of the endogenous cannabinoid anandamide was studied by …