… 2A–D). This promotes the idea that asRNAs may, at least in part, act independently of their
… 3D). Such variation in RNA folding allows the PTENpg1 alpha variant an alternative function, …

Metastasis is a multistep process beginning with the dissemination of tumor cells from a
primary site and leading to secondary tumor development in an anatomically distant location. …

… The different isoforms of Fbxw7 interact in vivo through association of their D-box motifs
located in the NH 2 -terminal region of the protein, and this interaction enhances SCF Fbxw7 -…

In recent decades we have been given insight into the process that transforms a normal cell
into a malignant cancer cell. It has been recognised that malignant transformation occurs …

PTEN is a tumor-suppressor gene that has been shown to be under the regulatory control of
a PTEN pseudogene expressed noncoding RNA, PTENpg1. Here, we characterize a …

Changes in genomic DNA methylation are recognized as important events in normal and
pathological cellular processes, contributing both to normal development and differentiation as …

… (d) Correlation of PML induction with cell death in primary CLL cells. Cells from nine patients
sensitive ex vivo to Dex-induced cell death and from two resistant patients were analyzed …

… A rearranged band (R) of about 17 kb in size was seen in CLL 4 and CLL 5; (d) the p32.3
marker was homozygously deleted in 183-E95, whereas CLL 4 showed no deletion and CLL 5 …

Interferon alpha (IFNα) has been used in the treatment of several types of cancer for almost
30 years, yet the mechanism (s) responsible for its anti-tumoral action remains unknown. A …

The latest revision of the WHO classification recognizes anaplastic lymphoma kinase-negative
(ALK-) anaplastic large-cell lymphoma (ALCL), as a distinct type of mature T-cell …