Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B.

…, S Singh, TR Burke Jr, D Grunberger… - Proceedings of the …, 1996 - National Acad Sciences
Caffeic acid phenethyl ester (CAPE), an active component of propolis from honeybee hives,
is known to have antimitogenic, anticarcinogenic, antiinflammatory, and immunomodulatory …

[BOOK][B] Molecular biology of mutagens and carcinogens

B Singer, D Grunberger - 2012 - books.google.com
This book originated in numerous Gordon Research Conferences and many other meetings
of scientists working in chemistry, biophysics, biochemistry, and biology related to …

Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation

…, BS Zweifel, C Koboldt, JR Mestre, D Grunberger… - Cancer research, 1999 - AACR
We investigated the mechanisms by which caffeic acid phenethyl ester (CAPE), a phenolic
antioxidant, inhibited the stimulation of prostaglandin (PG) synthesis in cultured human oral …

Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis

NN Mahmoud, AM Carothers, D Grunberger… - …, 2000 - academic.oup.com
Epidemiological studies consistently indicate that consumption of fruits and vegetables
lowers cancer risk in humans and suggest that certain dietary constituents may be effective in …

Inhibition of tumor promoter-mediated processes in mouse skin and bovine lens by caffeic acid phenethyl ester

…, MT Huang, T Ferraro, AH Conney, D Grunberger - Cancer Research, 1993 - AACR
Caffeic acid phenethyl ester (CAPE) was isolated from propolis (a product of honeybee hives)
that has been used in folk medicine as a potent antiinflammatory agent. CAPE is cytotoxic …

Hydroxylated aromatic inhibitors of HIV-1 integrase

…, J Wang, AM Carothers, D Grunberger… - Journal of Medicinal …, 1995 - ACS Publications
Efficient replication of HIV-1 requires integration of a DNA copy of the viral genome into a
chromosome of the host cell. Integration is catalyzed bythe viral integrase, and we have …

Apoptosis and altered redox state induced by caffeic acid phenethyl ester (CAPE) in transformed rat fibroblast cells

C Chiao, AM Carothers, D Grunberger, G Solomon… - Cancer Research, 1995 - AACR
Caffeic acid phenethyl ester (CAPE), which is derived from the propolis of bee hives, was
shown previously to block tumor promoter- and carcinogen-generated oxidative processes in …

Inhibition of oxidative stress in HeLa cells by chemopreventive agents

RS Bhimani, W Troll, D Grunberger, K Frenkel - Cancer Research, 1993 - AACR
12-O-Tetradecanoylphorbol-13-acetate (TPA)-mediated oxidative stress in HeLa cells and its
inhibition were studied by fluorometric measurement of H 2 O 2 and by 3 H-postlabeling of …

Inhibitory effects of caffeic acid phenethyl ester (CAPE) on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in mouse skin …

…, W Ma, P Yen, JG Xie, J Han, K Frenkel, D Grunberger… - 1996 - academic.oup.com
Topical application of caffeic acid phenethyl ester (CAPE), a constituent of the propolis of
honeybee hives, to the backs of CD-1 mice previously initiated with 7, 12-dimethylbenz[α]…

Inhibitory effects of topical application of low doses of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and oxidized DNA bases in mouse …

…, P Yen, JG Xie, J Han, K Frenkel, D Grunberger… - …, 1997 - academic.oup.com
The effects of topical applications of very low doses of curcumin (the major yellow pigment
in turmeric and the Indian food curry) on 12-O-tetradecanoylphorbol-13-acetate (TPA)-…