We conducted a mutational analysis of residues potentially involved in the adenine nucleotide
binding pocket of the human P2Y 1 receptor. Mutated receptors were expressed in COS-7 …

The molecular basis for recognition by human P2Y 1 receptors of the novel, competitive
antagonist 2‘-deoxy-N 6 -methyladenosine 3‘,5‘-bisphosphate (MRS 2179) was probed using …

Post‐traumatic osteoarthritis (PTOA) is characterized by progressive cartilage degeneration
in injured joints. Since fibronectin‐fragments (Fn‐fs) degrade cartilage mainly through up‐…

Simple Summary We have shown that Clear Cell Renal Cell Carcinoma (ccRCC) is prone
to accumulate poly(ADPribose) due to increase in PARP-1 and decrease in PARG enzymes. …

Wavelet packet transform is an effective texture analysis approach by sub-band filtering.
Different texture patterns have distinctive responses to the sub-bands of wavelet packets. The …

Chemokines are highly expressed in tumor microenvironment and play a critical role in all
aspects of tumorigenesis, including the recruitment of tumor-promoting immune cells, …

Poly(ADP-ribose) polymerase 1 (PARP-1) is a nuclear enzyme involved in DNA repair and
transcription regulation, among other processes. Malignant transformations, tumor …

Site‐directed mutagenesis was used to search for amino acid residues of the human P2Y 1
receptor involved in the binding of the P2 receptor antagonists pyridoxal‐5′‐phosphate‐6‐…

Object categorization plays an important role in computer vision, semantic based image
content understanding, and image retrieval. Wavelet packet transform provides a very good …

Post-translational modification of nuclear proteins through the addition of poly(ADP-ribose) (pADPr)
moieties is upregulated in many metastatic cancers, where the high levels of pADPr …