Cytotoxic properties of the eosinophil major basic protein
GJ Gleich, E Frigas, DA Loegering… - The Journal of …, 1979 - journals.aai.org
The eosinophil major basic protein (MBP) damages cells including those from organs whose
dysfunction is associated with eosinophil infiltration. Concentrations of MBP in the toxic …
dysfunction is associated with eosinophil infiltration. Concentrations of MBP in the toxic …
Toxicity of Eosinophil Cationic Proteins for Guinea Pig Tracheal Epithelium In Vifr01
S Motojima, E Frigas, DA Loegering, GJ Gleich - Am Rev Respir Dis, 1989 - atsjournals.org
We tested the effects of four eosinophil granule cationic proteins: major basic protein (MBP),
eosinophil cationic protein (ECP), eosinophil peroxidase (EPO), and eosinophil-derived …
eosinophil cationic protein (ECP), eosinophil peroxidase (EPO), and eosinophil-derived …
Biochemical and functional similarities between human eosinophil-derived neurotoxin and eosinophil cationic protein: homology with ribonuclease.
GJ Gleich, DA Loegering, MP Bell… - Proceedings of the …, 1986 - National Acad Sciences
Eosinophil-derived neurotoxin (EDN) and eosinophil cationic protein (ECP) were isolated
from lysates of human eosinophil granules by gel filtration and ion exchange chromatography …
from lysates of human eosinophil granules by gel filtration and ion exchange chromatography …
[HTML][HTML] An investigation of the cause of the eosinophilia–myalgia syndrome associated with tryptophan use
…, KE White, AN Mayeno, DA Loegering… - … England Journal of …, 1990 - Mass Medical Soc
Background. The eosinophilia—myalgia syndrome is a newly recognized illness that has
been associated with the consumption of tryptophan products. It is not known whether the …
been associated with the consumption of tryptophan products. It is not known whether the …
Damage to Schistosomula of Schistosoma Mansoni Induced Directly by Eosinophil Major Basic Protein
…, GJ Gleich, DA Loegering, JR David - Journal of …, 1979 - journals.aai.org
Major basic protein (MBP) from both human and guinea pig eosinophils has been found to
damage schistosomula of Schistosoma mansoni at concentrations as low as 2 × 10 -5 M. This …
damage schistosomula of Schistosoma mansoni at concentrations as low as 2 × 10 -5 M. This …
Ribonuclease activity associated with human eosinophil-derived neurotoxin and eosinophil cationic protein.
NR Slifman, DA Loegering, DJ McKean… - Journal of immunology …, 1986 - journals.aai.org
The eosinophil granule contains a series of basic proteins, including major basic protein,
eosinophil peroxidase, eosinophil-derived neurotoxin (EDN), and eosinophil cationic protein (…
eosinophil peroxidase, eosinophil-derived neurotoxin (EDN), and eosinophil cationic protein (…
Eosinophil granule proteins in peripheral blood granulocytes
…, SL Dunnette, DA Loegering… - Journal of leukocyte …, 1992 - Wiley Online Library
Eosinophils contain four principal cationic proteins, major basic protein (MBP), eosinophil‐derived
neurotoxin (EDN), eosinophil cationic protein (ECP), and eosinophil peroxidase (EPO)…
neurotoxin (EDN), eosinophil cationic protein (ECP), and eosinophil peroxidase (EPO)…
Purification of human eosinophil-derived neurotoxin.
…, SJ Ackerman, DA Loegering… - Proceedings of the …, 1981 - National Acad Sciences
Human and animal eosinophils contain a powerful neurotoxin that causes selective neuronal
and axonal damage to white matter of cerebellum and spinal cord of experimental animals …
and axonal damage to white matter of cerebellum and spinal cord of experimental animals …
In vitro and In vivo Antitumor Effects of the Dual Insulin-Like Growth Factor-I/Insulin Receptor Inhibitor, BMS-554417
P Haluska, JM Carboni, DA Loegering, FY Lee… - Cancer research, 2006 - AACR
The insulin-like growth factor receptor (IGF-IR) and insulin receptor are either overactivated
and/or overexpressed in a wide range of tumor types and contribute to tumorigenicity, …
and/or overexpressed in a wide range of tumor types and contribute to tumorigenicity, …
Immunobiology of eosinophils
GJ Gleich, DA Loegering - Annual review of immunology, 1984 - annualreviews.org
The eosinophilic leukocyte was discovered by Paul Ehrlich in 1879 when he stained fixed
blood smears with aniline dyes (1). By the early part of this century a voluminous literature on …
blood smears with aniline dyes (1). By the early part of this century a voluminous literature on …