Recent studies suggested contribution of homocysteine (HCY) to neurodegenerative disorders
and migraine. However, HCY effect in the nociceptive system is essentially unknown. To …

Diverse subtypes of nicotinic acetylcholine receptors (nAChRs), including fast-desensitizing
α7-containing receptors thought to be Ca 2+ -permeable, are expressed in the CNS, where …

Long-term neural differentiation of human pluripotent stem cells (hPSCs) is associated with
enhanced neuronal maturation, which is a necessity for creation of representative in vitro …

Extracellular ATP is suspected to contribute to migraine pain but regulatory mechanisms
controlling pro-nociceptive purinergic mechanisms in the meninges remain unknown. We …

Neuronal nicotinic acetylcholine receptors (nAChRs) are involved in cognition and may play
a role in Alzheimer's disease (AD). Known inhibitors of acetylcholinesterase (AChE) are …

Intrinsic optical signals (IOSs) induced by synaptic stimulation and moderate hypotonic swelling
in brain tissue slices consist of reduced light scattering and are usually attributed to cell …

Neuronal nicotinic acetylcholine receptors (nAChRs) are widely expressed in the brain
where they are involved in a variety of physiological processes, including cognition and …

Neuronal nicotinic acetylcholine receptors (nAChRs) are in the superfamily of Cys‐loop
ligand‐gated ion channels, which are widely expressed in the brain. Among the many different …

J. Neurochem. (2011) 119, 676–685. Abstract Tyrosine 37 in the first transmembrane (TM1)
domain is highly conserved in ATP‐gated P2X receptors suggesting its fundamental role. …

ATP-gated P2X3 receptors are expressed by nociceptive neurons and participate in transduction
of pain. Responsiveness of P2X3 receptors is strongly reduced at low temperatures, …