User profiles for Duane D. Miller
Duane D. MillerUniversity of Tennessee College of Pharmacy Verified email at uthsc.edu Cited by 39153 |
An overview of tubulin inhibitors that interact with the colchicine binding site
Tubulin dynamics is a promising target for new chemotherapeutic agents. The colchicine
binding site is one of the most important pockets for potential tubulin polymerization …
binding site is one of the most important pockets for potential tubulin polymerization …
Structural basis for antagonism and resistance of bicalutamide in prostate cancer
CE Bohl, W Gao, DD Miller, CE Bell… - Proceedings of the …, 2005 - National Acad Sciences
Carcinoma of the prostate is the most commonly diagnosed cancer in men. The current
pharmacological treatment of choice for progressive androgen-dependent prostate cancer is the …
pharmacological treatment of choice for progressive androgen-dependent prostate cancer is the …
Emerging trends in oral delivery of peptide and protein drugs
…, AS Narang, L Thoma, DD Miller - Critical Reviews™ in …, 2003 - dl.begellhouse.com
Most peptide and protein drugs are currently used as parenteral formulations because of
their poor oral bioavailability. Development of an effective oral delivery system for these …
their poor oral bioavailability. Development of an effective oral delivery system for these …
Discovery of nonsteroidal androgens
…, A Mukherjee, Z Zhu, L Kirkovsky, DD Miller - … and biophysical research …, 1998 - Elsevier
Nonsteroidal androgens have not been reported. During studies to identify affinity ligands for
the androgen receptor in our laboratory, we synthesized several electrophilic nonsteroidal …
the androgen receptor in our laboratory, we synthesized several electrophilic nonsteroidal …
Novel branched poly (Ethylenimine)− cholesterol water-soluble lipopolymers for gene delivery
…, AS Narang, M Kotb, AO Gaber, DD Miller… - …, 2002 - ACS Publications
A novel water-soluble lipopolymer was synthesized by linking cholesteryl chloroformate to
the secondary amino groups of branched poly(ethylenimine) (PEI) of 1800 and 10000 Da. …
the secondary amino groups of branched poly(ethylenimine) (PEI) of 1800 and 10000 Da. …
Direct quantitative analysis of lysophosphatidic acid molecular species by stable isotope dilution electrospray ionization liquid chromatography–mass spectrometry
In order to better understand the role of lysophosphatidic acid (LPA) in physiology and
pathophysiology, it is necessary to accurately determine the molecular species and amounts of …
pathophysiology, it is necessary to accurately determine the molecular species and amounts of …
Favorable effects of weak acids on negative-ion electrospray ionization mass spectrometry
Despite widespread use in pharmacokinetic, drug metabolism, and pesticide residue studies,
little is known about the factors governing response during reversed-phase liquid …
little is known about the factors governing response during reversed-phase liquid …
[HTML][HTML] Structural basis for accommodation of nonsteroidal ligands in the androgen receptor
CE Bohl, DD Miller, J Chen, CE Bell… - Journal of biological …, 2005 - ASBMB
The mechanism by which the androgen receptor (AR) distinguishes between agonist and
antagonist ligands is poorly understood. AR antagonists are currently used to treat prostate …
antagonist ligands is poorly understood. AR antagonists are currently used to treat prostate …
Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit
Interest in the development and therapeutic potential of nonsteroidal tissue-selective
androgen receptor modulators (SARMs) a has increased dramatically within the past decade. …
androgen receptor modulators (SARMs) a has increased dramatically within the past decade. …
Synthesis and antiproliferative activity of 2-aryl-4-oxo-thiazolidin-3-yl-amides for prostate cancer
We have previously described serine amide phosphates (SAPs) as a novel class of cytotoxic
agents for prostate cancer. Several of them showed potent cytotoxicity against human …
agents for prostate cancer. Several of them showed potent cytotoxicity against human …