Enzyme-labeling of antibodies and their fragments for enzyme immunoassay and immunohistochemical staining

E Ishikawa, M Imagawa, S Hashida… - … of Immunoassay and …, 1983 - Taylor & Francis
… is much more stable at pH 7 than N,N'-o-phenylenedimaleimide in which the maleimide
group is directly attached to a benzene ring stimulated us to synthesize a more s ta bl e ma 1 ei …

Recognition of mycobacterial lipids by immune receptors

E Ishikawa, D Mori, S Yamasaki - Trends in immunology, 2017 - cell.com
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), infects one-third
of the world's population and causes 1.5 million deaths each year. The cell envelopes of …

[PDF][PDF] Th17 cell induction by adhesion of microbes to intestinal epithelial cells

…, A Imaoka, H Setoyama, T Nagamori, E Ishikawa… - Cell, 2015 - cell.com
… in feces and SI mucosal tissues by qPCR (Figure 1E). Examination of the rat SI mucosal …
-SFB DNA in the feces was comparable (Figures 1E and 1F). We then investigated the effects of …

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

E Ishikawa, T Ishikawa, YS Morita… - Journal of experimental …, 2009 - rupress.org
Tuberculosis remains a fatal disease caused by Mycobacterium tuberculosis, which
contains various unique components that affect the host immune system. Trehalose-6,6′-…

Mincle is an ITAM-coupled activating receptor that senses damaged cells

S Yamasaki, E Ishikawa, M Sakuma, H Hara… - Nature …, 2008 - nature.com
… (d,e) Flow cytometry of neutrophils among (d) and cytokine production by (e) peritoneal
exudate cells from mice given 0.5 mg rat IgG or anti-Mincle (1B6 or 4A9) intravenously, then …

Ovarian atypical endometriosis: its close association with malignant epithelial tumours

M Fukunaga, K Nomura, E Ishikawa… - …, 1997 - Wiley Online Library
The incidence of ovarian atypical endometriosis and its association with malignant epithelial
tumours in a consecutive series of cases during the period 1987 to 1995 were studied. …

Early colorectal carcinoma with special reference to its development de novo

…, J Fujisaki, T Matsui, S Aizawa, E Ishikawa - Cancer, 1989 - Wiley Online Library
The growth type of early colorectal carcinoma was classified into two types. The first type is
intramucosal polypoid growth (PG‐Ca) and the second type nonpolypoid growth (NPG‐Ca) …

C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance

…, M Nakane, K Kage, S Tsukahara, E Ishikawa… - Molecular cancer …, 2002 - AACR
… Because lysine and glutamine have different electronic charges, substitution of lysine for
glutamine might alter the tertiary structure of BCRP protein, leading to greater susceptibility to …

A phase I study of α-galactosylceramide (KRN7000)–pulsed dendritic cells in patients with advanced and recurrent non–small cell lung cancer

A Ishikawa, S Motohashi, E Ishikawa, H Fuchida… - Clinical Cancer …, 2005 - AACR
Purpose: Human Vα24 natural killer T (NKT) cells bearing an invariant Vα24JαQ antigen
receptor, the counterpart of murine Vα14 NKT cells, are activated by a specific ligand, α-…

[HTML][HTML] Early-life events, including mode of delivery and type of feeding, siblings and gender, shape the developing gut microbiota

…, K Ben-Amor, M Roelofs, E Ishikawa… - PloS one, 2016 - journals.plos.org
Colonization of the infant gut is believed to be critically important for a healthy growth as it
influences gut maturation, metabolic, immune and brain development in early life. …