User profiles for E. Makonnen

Eyasu Makonnen

Professor of Pharmacology, Addis Ababa University
Verified email at aau.edu.et
Cited by 6132

[HTML][HTML] Systematic review of Ethiopian medicinal plants used for their anti-inflammatory and wound healing activities

D Nigussie, E Makonnen, TB Tufa, M Brewster… - Journal of …, 2021 - Elsevier
… Similarly, percent a n t i − i n f l a m m a t o r y = % I c − % I e % I c x 100 where %I c and %I
e are the mean inflammation values reached in the control and experimental groups, …

[HTML][HTML] Sodium stibogluconate (SSG) & paromomycin combination compared to SSG for visceral leishmaniasis in East Africa: a randomised controlled trial

…, H Tafes, Y Mekonnen, E Makonnen… - PLoS neglected …, 2012 - journals.plos.org
Background Alternative treatments for visceral leishmaniasis (VL) are required in East Africa.
Paromomycin sulphate (PM) has been shown to be efficacious for VL treatment in India. …

[HTML][HTML] Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

…, AJ Fawcett, C Gruber, EG Mekonnen, E Mixter… - Nature medicine, 2023 - nature.com
Precision medicine is part of the logical evolution of contemporary evidence-based medicine
that seeks to reduce errors and optimize outcomes when making medical decisions and …

Essential oils as topical anti-infective agents: A systematic review and meta-analysis

…, AG Mtewa, A Abebe, A Hymete, E Makonnen… - … therapies in medicine, 2019 - Elsevier
Objective This study summarized evidence on the efficacy and safety of essential oils (EOs)
in the treatment of topical infections. Design and setting Systematic review of clinical trials …

In vitro and in vivo anthelmintic activity of crude extracts of Coriandrum sativum against Haemonchus contortus

…, G Tilahun, A Debella, A Feleke, E Makonnen - Journal of …, 2007 - Elsevier
In vitro anthelmintic activities of crude aqueous and hydro-alcoholic extracts of the seeds of
Coriandrum sativum (Apiaceae) were investigated on the egg and adult nematode parasite …

Evaluation of in vivo wound healing activity of methanol extract of Achyranthes aspera L.

A Fikru, E Makonnen, T Eguale, A Debella… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: The leaves of Achyranthes aspera L. (Amarenthacea)
has been used traditionally for the treatment of wound in various parts of Ethiopia. …

Genetic polymorphism of CYP1A2 in Ethiopians affecting induction and expression: characterization of novel haplotypes with single-nucleotide polymorphisms in …

E Aklillu, JA Carrillo, E Makonnen, K Hellman… - Molecular …, 2003 - ASPET
CYP1A2 polymorphism has been well studied in white persons and Asians but not in Africans.
We performed CYP1A2 genotype and phenotype analysis using caffeine in Ethiopians …

[HTML][HTML] Intestinal α-glucosidase and some pancreatic enzymes inhibitory effect of hydroalcholic extract of Moringa stenopetala leaves

A Toma, E Makonnen, Y Mekonnen, A Debella… - … and alternative medicine, 2014 - Springer
Background Moringa stenopetala has been used in traditional health systems to treat diabetes
mellitus. One of the successful methods to prevent of the onset of diabetes is to control …

[HTML][HTML] Antidiabetic activities of aqueous ethanol and n-butanol fraction of Moringa stenopetala leaves in streptozotocin-induced diabetic rats

A Toma, E Makonnen, Y Mekonnen, A Debella… - … and alternative medicine, 2015 - Springer
Background Moringa stenopetala has been used in traditional health systems to treat
diabetes mellitus. The aim of this study was to investigate the antidiabetic activity of aqueous …

Hypoglycaemic Effect of Moringa stenopetala Aqueous Extract in Rabbits

E Makonnen, A Hunde… - … Research: An International …, 1997 - Wiley Online Library
The hypoglycaemic effect of Moringa stenopetala extract was assessed in nondiabetic rabbits
by blood glucose analysis. In vivo experiments were carried out in rabbits that received the …